介入性超声治疗甲状腺良性结节的临床应用

【摘要】 目的 评价介入性超声治疗甲状腺良性结节的临床应用价值。方法 246例甲状腺良性结节的患者在超声介入下进行无水乙醇或32P胶体局部注射治疗，3个月和12个月后评价治疗疗效。结果 无水乙醇硬化治疗及32P胶体治疗均有明显的疗效，3个月和12个月总有效率分别为91.8%和93.4% 和91.9%，96.8%，两者无明显差异（P>0.05）。囊性病变疗效好于实性病变，12个月总有效率分别为100%和85.0%（P<0.01）；32P胶体治疗实性病变稍优于无水乙醇治疗，12个月总有效率分别为90.9 %和77.8%（P<0.05）；对于囊性病变，两种治疗方法的效果并无显著性差异（P<0.05）。结论 介入性超声在治疗甲状腺良性结节中具有实用临床价值。

Clinical application of interventional ultrasound therapy in thyroid benign nodules

【Abstract】 Objective To evaluate the clinical application value of interventional ultrasound therapy in thyroid benign nodules. Methods 246 patients with thyroid benign nodules were treated with Percutaneous ethnol injection(PEI)and radioactive colloidal chromium phosphated-32(RCCP)under the guidance of ultrasound, and the therapeautical results were evaluated 3 m and 12m post-treatment. Results Both ethnol and radioactive colloidal chromium phosphate-32 had significant effects in reducing the nodule size, the total effective rate was 91.8% , 93.4%and91.9% , 96.8%post 3m and 12m respectively, there was no obvious difference(P>0.05).But there was better effect in the solid lesion than in the others, the total effective rate was 100% and 85.0% respectively post 12m therapy(P<0.01).But for the solid lesion,PEI was superior to RCCP, the effective rate was90.9% and 77.8%(P<0.05),but no difference between both methods in cyst lesions. Conclusion Interventional ultrasound therapy had practical clinical value in the treatment of thyroid benign nodules.