| 幽门螺杆菌与反流性食管炎发病关系的探讨 |
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| 引用本文： | 王少鑫,刘超群,浦江,付山峰,岳鑫. 幽门螺杆菌与反流性食管炎发病关系的探讨[J]. 中国医药, 2009, 4(11): 868-869. DOI: 10.3760/cma.j.issn.1673-4777.2009.11.017 |
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| 作者姓名： | 王少鑫 刘超群 浦江 付山峰 岳鑫 |
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| 作者单位： | 海军总医院消化科,北京,100037 |
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| 摘 要： | 目的探讨幽门螺杆菌（Hp）与反流性食管炎（RE）发病的关系。方法回顾性分析2004年1月至2008年5月行胃镜检查患者的报告，将内镜下RE阳性286例患者作为研究组进行分级，选择同期行内镜检查的非RE慢性胃炎250例患者为对照组，统计2组Hp阳性率并进行比较。结果研究组Hp感染率为28．7％（82／286），明显低于对照组的48．4％（121／250）（χ^2=21．01，P=0．00）。研究组中无论是否存在Hp感染均以轻度食管炎多见，而且其Hp感染率32．0％要高于重度食管炎17．2％，组间比较差异有统计学意义（χ^2=5．153，P〈0．05）。结论Hp在食管炎的发病过程中与消化性溃疡等疾病不同，并非主要致病因素。
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| 关 键 词： | 反流性食管炎 幽门螺杆菌 病因学 |
Relation between H. pylori and reflux esophagitis'pathogeny |
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| WANG Shao-xin,LIU Chao-qun,PU Jiang,FU Shan-feng,YUE Xin. Relation between H. pylori and reflux esophagitis'pathogeny[J]. China Medicine, 2009, 4(11): 868-869. DOI: 10.3760/cma.j.issn.1673-4777.2009.11.017 |
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| Authors: | WANG Shao-xin LIU Chao-qun PU Jiang FU Shan-feng YUE Xin |
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| Affiliation: | . (Department of Digestive Internal Medicine, Navy General Hospital, Beijing 100037, China) |
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| Abstract: | Objective To observe the relation between H. pylori and reflux esophagitis' pathogeny. Methods Gastroscopy reports on reflux esophagitis in the last four years were reviewed, reflux esophagitis was gra-ded and HP positive rate in different groups was calculated. Results The Hp positive rate(28.7%) in RE group was lower than that in control group. Low-grade esophagitis was primary in patients infected by Hp or not, with a higher Hp positive rate(32.0%)than high-grade esophagitis group(17.2%)(P<0.05) Conclusion Hp is not the main pathogeny of reflux esophagitis, which is different from peptic ulcer disease. |
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| Keywords: | Reflux esophagitis H. pylori Pathogeny |
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