| 输卵管妊娠药物介入治疗 |
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| 引用本文： | 张科荣,敬巧,范波,谌伦华,姜荣娅. 输卵管妊娠药物介入治疗[J]. 中华妇幼临床医学杂志(电子版), 2011, 7(1): 48-51. DOI: 10.3877/cma.j.issn.1673-5250.2011.01.014 |
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| 作者姓名： | 张科荣 敬巧 范波 谌伦华 姜荣娅 |
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| 作者单位： | 四川南充,637000,川北医学院附属医院妇产科 |
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| 摘 要： | 目的探讨输卵管妊娠药物介入治疗的可行性、适应证、禁忌证。方法选择1998年10月至2009年12月在本院经阴道超声检查明确诊断为输卵管妊娠且病灶直径<5cm患者374例为研究对象。对其进行药物介入治疗,利用输卵管介入再通装置,于输卵管内一次性注入甲氨蝶呤(methotrexate,MTX)100mg,并观察患者血清β-人绒毛膜促性腺激素(human chorionic gonadotrophin,hCG)下降、阴道流血、病灶消失、输卵管通畅度、妊娠及腹痛消失等情况(本研究遵循的程序符合本院人体试验委员会所制定的伦理学标准,得到该委员会批准,并与受试者签署临床研究知情同意书)。结果 365例阴道超声检查示妊娠物内无胚芽及心导管搏动的输卵管妊娠患者,接受介入治疗获成功;另外9例妊娠物内可见胚芽及心导管搏动患者接受介入治疗失败后,改行手术治疗终止妊娠。结论对病灶直径<5cm、阴道超声示妊娠物内无胚芽及心导管搏动的输卵管妊娠患者,患侧输卵管内一次性注入甲氨蝶呤100mg介入治疗疗效肯定,并可能保留输卵管功能。
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| 关 键 词： | 输卵管妊娠 药物介入治疗 甲氨蝶呤 |
Drug Intervention Treatment on Tubal Pregnancy |
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| ZHANG Ke-rong,JING Qiao,FAN Bo,CHEN Lun-hua,JIANG Rong-yan. Drug Intervention Treatment on Tubal Pregnancy[J]. Chinese JOurnal of Obstetrics & Gynecology and Pediatrics, 2011, 7(1): 48-51. DOI: 10.3877/cma.j.issn.1673-5250.2011.01.014 |
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| Authors: | ZHANG Ke-rong JING Qiao FAN Bo CHEN Lun-hua JIANG Rong-yan |
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| Affiliation: | ZHANG Ke-rong,JING Qiao,FAN Bo,CHEN Lun-hua,JIANG Rong-yan.Department of Obstetrics and Gynecology,Affiliated Hospital of North Sichuan Medical College,Nanchong 637000,Sichuan Province,China |
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| Abstract: | Objective To investigate the feasibility,indication and contraindications of drug intervention therapy on tubal pregnancy(TP).Methods From October 1998 to December 2009,374 cases of tubal pregnancy whose lesion less than 5 cm were injected methotrexate(MTX)100 mg of drug intervention therapy by the tubal dredging device in a one-time,and then observed the effects of treatment.The study protocol was approved by the Ethical Review Board of Investigation in Human Being of Affiliated Hospital of North Sichuan M... |
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| Keywords: | tubal pregnancy(TP) drug intervention therapy methotrexate(MTX) |
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