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大补阴丸对实验性甲亢大鼠胸腺病理改变的影响
引用本文:胡方林,刘仙菊,张国民,龙玲,阳春林.大补阴丸对实验性甲亢大鼠胸腺病理改变的影响[J].世界中西医结合杂志,2008,3(6):322-323.
作者姓名:胡方林  刘仙菊  张国民  龙玲  阳春林
作者单位:[1]湖南中医药大学,湖南长沙410208; [2]湖南中医药大学2006级研究生,湖南长沙410208
基金项目:湖南中医药大学校长基金
摘    要:目的:观察大补阴丸对实验性甲亢大鼠胸腺病理改变的影响。方法:用左甲状腺素钠(优甲乐)灌服造成大鼠甲亢模型,观察大补阴丸(汤剂)不同剂量内服对大鼠胸腺病理改变的影响。结果:大补阴丸低、中剂量组和西药组胸腺厚度明显增加,细胞数目增多,密度增大,网状细胞散在、成熟,小血管丰富充血,可见胸腺小体,其中大补阴丸高剂量组胸腺组织结构同正常组基本相同。结论:大补阴丸能改善甲亢大鼠胸腺病理改变。

关 键 词:大补阴丸  甲状腺机能亢进  大鼠  胸腺  病理

Effect of Dabuyinwan on Thymus Pathological Changes of Experimental Hyperthyroid Rats
HU Fang-lin,LIU Xian-ju,ZHANG Guo-min,LONG Ling,YANG Chun-lin.Effect of Dabuyinwan on Thymus Pathological Changes of Experimental Hyperthyroid Rats[J].World Journal Of Integrated Traditional and Wesrern Medicine,2008,3(6):322-323.
Authors:HU Fang-lin  LIU Xian-ju  ZHANG Guo-min  LONG Ling  YANG Chun-lin
Affiliation:HU Fang-lin, LIU Xian-ju,ZHANG Guo-min, LONG Ling,YANG Chun-lin (Hunan University of TCM, Changsha Hunan 410208;Hunan University of TCM 2006 Graduate Student, Changsha Hunan 410208)
Abstract:Objective:To observe the effect of Dabuyinwan on thymus pathological changes of experimental hyperthyroid rats. Methods:Hyperthyroid rats were induced by Euthyrox given orally everyday for three weeks. Then the effect of Dabuyinwan on thymus pathological changes was observed. Results:The thymus thickness, cells numbers, density increased significantly in low,middle and large dosgage of Dabuyinwan groups. Reticular cells scattered and matured, small vessels congestived obviously, there were thymic corpuscles. The groups of high dose Dabuyinwan had basically the same thymus tissue structure as the normal group. Conclusion:Dabuyinwan had the effect of improving thymus pathology of experimental hyperthyroid rat.
Keywords:Dabuyinwan  hyperthyreosis  rats  thymus  pathological changes
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