07H239-A, a new cytotoxic eremophilane sesquiterpene from the marine-derived Xylariaceous fungus LL-07H239 |
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| Authors: | McDonald Leonard A Barbieri Laurel R Bernan Valerie S Janso Jeffrey Lassota Peter Carter Guy T |
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| Affiliation: | Wyeth-Research, 401 North Middletown Road, Pearl River, New York 10965, USA. mcdonal@wyeth.com |
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| Abstract: | 07H239-A (1), a new eremophilane sesquiterpene from a marine-derived xylariaceous fungus, was isolated, characterized, and shown to be cytotoxic toward a variety of cancer cell lines, with some selectivity for a CCRFCEM leukemia line (IC(50) = 0.9 microg/mL). |
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