蜗牛卵液对小鼠S_(180)肉瘤的抑制作用

[目的 ]探讨蜗牛卵液对小鼠S180 肉瘤的抑制作用 .[方法 ]按标准方法给 4 0只小鼠接种S180肉瘤细胞后 ,随机分成 4个组 ,即对照组 :每日灌胃生理盐水 10mL/kg ;实验 1组 :每日灌胃蜗牛卵液1 5 g/kg ;实验 2组 :每日灌胃蜗牛卵液 3 0 g/kg ;实验 3组 :每日灌胃蜗牛卵液 3 8g/kg ;连续 8d后 ,观察肿瘤质量变化及胸腺 (脾脏 )指数 .[结果 ]每日 1 5 ,3 0 ,3 8g/kg的蜗牛卵液对小鼠S180 肉瘤的生长抑制率分别为 38 2 % ,4 0 5 % ,5 4 4 % ,实验 3组的肿瘤抑制率高于对照组 ,两组间有显著性差异 ;实验2组和实验 3组的胸腺 (脾脏 )指数低于对照组 ,与对照组相比较亦有显著性差异 .[结论 ]蜗牛卵液对小鼠S180 肉瘤有抑制作用 .

Inhibition effects of the snail ovum on the mice S-180 sarcoma

OBJECTIVE?To investigate the anti -tumor ef fects of snail ovum.?METHODS?After inoculatiing of the S-180 sarcoma cells to 40 cases of mice, and all cases were divided into four groups t hat the control group was perfused every day with 10?mL/kg of physiological sal ine, and group 1, group 2 and group 3 were perfused every day with 1.5, 3.0 an d 3.8?g/kg of snail ovum, respectively. 8 days later, the weight of tumor and the index of thymus (spleen) were detected.?RESULTS?Inhib itio n ratio of the snail ovum concentrated 1.5, 3.0 and 3.8?g/kg were 38.2%, 40 .5% and 54.4% on the growth of S-180 sarcoma cells, respectively. The inhib ition rate of group 3 was higher than that of the control, but the spleen inde xes of both group 2 and group 3 were lower than that of the control.?CON CLUSION?The snail ovum inhibites the growth of S-180 sarcoma cells.