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A convergent approach to the formal total synthesis of hemibrevetoxin B |
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| Authors: | Isao Kadota Takashi Abe Abeda S. Touchy Yoshinori Yamamoto |
| Affiliation: | a Department of Chemistry, Graduate School of Natural Science and Technology, Okayama University, 3-1-1 Tsushima-naka, Okayama 700-8530, Japan b Department of Chemistry, Graduate School of Science, Tohoku University, Sendai 980-8578, Japan |
| Abstract: | A convergent synthesis of the key synthetic intermediate of hemibrevetoxin B was achieved via the intramolecular allylation of an α-chloroacetoxy ether and subsequent ring-closing metathesis. |
| Keywords: | Hemibrevetoxin B Polycyclic ethers Convergent synthesis |
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