Maternal Reproductive Toxicity of Some Essential Oils and Their Constituents |
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Authors: | Noura S. Dosoky William N. Setzer |
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Affiliation: | 1.Aromatic Plant Research Center, Lehi, UT 84043, USA;2.Department of Chemistry, University of Alabama in Huntsville, Huntsville, AL 35899, USA; |
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Abstract: | Even though several plants can improve the female reproductive function, the use of herbs, herbal preparations, or essential oils during pregnancy is questionable. This review is focused on the effects of some essential oils and their constituents on the female reproductive system during pregnancy and on the development of the fetus. The major concerns include causing abortion, reproductive hormone modulation, maternal toxicity, teratogenicity, and embryo-fetotoxicity. This work summarizes the important studies on the reproductive effects of essential oil constituents anethole, apiole, citral, camphor, thymoquinone, trans-sabinyl acetate, methyl salicylate, thujone, pulegone, β-elemene, β-eudesmol, and costus lactone, among others. |
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Keywords: | essential oils pregnancy anethole trans-sabinyl acetate camphor methyl salicylate thujone pulegone citral apiole |
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