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不同评估方法在T2DM心血管病风险评估中的应用
作者姓名:陈珮琪  杨宗璐  赵玲  杜士刚  杨璐  李诗雨  戴雨如  柯亭羽
作者单位:昆明医科大学第二附属医院内分泌科,云南 昆明 650101
基金项目:国家自然科学基金资助项目(81760327);云南省医学领军人才基金资助项目(L-2019014);昆明医科大学研究生创新基金资助项目(2021S061);昆明医科大学第二附属医院院内科技计划基金资助项目(2020yk005)
摘    要:目的 分析Framinghan、ADVANCE-Risk评分表与"糖心风险评估"、"CV风险评估"模型评估对T2DM患者未来10 a心血管疾病死亡风险评估的一致性.方法 回顾性收集昆明医科大学第二附属医院内分泌科2018年1月至2020年12月符合2型糖尿病诊断标准住院患者527例:(1)使用"糖心风险评估"模型与Fr...

关 键 词:2型糖尿病  心血管疾病  风险评估
收稿时间:2021-12-01

Application of Different Assessment Methods in Cardiovascular Disease Risk Assessment of T2DM
Affiliation:Dept. of Endocrinology,The 2nd Affiliated Hospital of Kunming Medical University, Kunming Yunnan 650101, China
Abstract:  Objective  To analyze the consistency between the Framinghan, the advance-risk scale and the “sugar-heart risk assessment”, the “CV risk assessment” model on the risk of cardiovascular death in T2DM patients in the next 10 years.   Methods  A retrospective study of 527 inpatients who met the diagnostic criteria for type 2 diabetes in the Department of Endocrinology, The Second Affiliated Hospital of Kunming Medical University from January 2018 to December 2020 was conducted. The Framinghan rating scale and the Cardiovascular risk assessment for diabetes mellitus model were used to assess the occurrence risk of cardiovascular disease over the next 10 years. 148 patients with increased diabetes duration, UACR and other indicators were included. ADVANCE Risk score and CV Risk Assessment project were used to evaluate the risk of cardiovascular death of the same patient in the next 10 years. Kappa values were used to evaluate the consistency of the results of the two methods.   Results   The result of Cardiovascular risk assessment for diabetes mellitus model: 431 patients (81.78%) in the medium-risk group, and 250 patients (47.44%) in the high-risk group using Framinghan rating scale. SPSS analysis showed Kappa value, K = 0.051, P = 0.001; The result of CV Risk assessment”: 98 patients (66.22%) in the very high Risk group, and 76 patients (50%) in the ADVANCE Risk model. SPSS analysis showed Kappa value, K = 0.492, P = 0.000.   Conclusion  In this study, the “Cardiovascular risk assessment for diabetes mellitus” model and Framinghan rating scale in assessing the occurrence risk of cardiovascular disease in patients with type 2 diabetes in the next 10 years were very inconsistent. The “CV Risk assessment” and ADVANCE Risk model had moderate consistency in assessing the mortality risk of cardiovascular in patients with type 2 diabetes over the next 10 years.
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