芪苈强心胶囊联合米力农治疗慢性心力衰竭的临床研究

目的 评价芪苈强心胶囊联合米力农治疗慢性心力衰竭的临床疗效.方法 选取2018年1月-2020年6月内蒙古包钢医院慢性心力衰竭患者140例作为研究对象,随机将患者分为对照组和观察组,每组各70例.对照组以米力农注射液0.5 μg/(kg·min)持续泵入72h,继以0.5μg/(kg·min)每日1次泵入,共4d.观察...

Clinical study of Qiliqiangxin Capsules combined with milrinone in treatment of chronic heart failure

Objective To evaluate the clinical effect of Qiliqiangxin Capsules combined with milrinone in treatment of chronic heart failure.Methods A total of 140 patients with chronic heart failure from January 2018 to June 2020 in Baogang Hospital of Inner Mongolia were selected as the research subjects,patients were randomly divided into control group and observation group,with 70 patients in each group.Patients in the control group were continuously pumped with Milrinone Injection of 0.5 g/(kg·min)for 72 h,and continued to be pumped every once for 4 days.Patients in the observation group were po administered with Qiliqiangxin Capsules on the basis of control group,3 grains/time,three times daily.The course of treatment in both groups was 7 days.The clinical efficacy of two groups was observed,and the levels of BNP,NT-proBNP,hs-CRP,IL-6,Cys-C,and LVEF,LVED before and after treatment were compared.Results After treatment,the total effective rate of the control group and the observation group was85.7%and 97.1%,respectively,the total effective rate difference between two groups was statistically significant(P<0.05).After treatment,the levels of BNP,NT-proBNP,hs-CRP,IL-6,Cys-C,and LVED in two groups were significantly decreased,but LVEF was significantly increased(P<0.05).After treatment,the above indexes in the observation group were significantly better than those in the control group,and the difference was statistically significant(P<0.05).Conclusion Qiliqiangxin Capsules combined with milrinone in treatment of chronic heart failure is effective,and tolerability is good,with clinical application and promotion value.