| 豚鼠圆窗膜破裂引起耳蜗形态变化的探讨 |
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| 引用本文： | 刘秀丽,别旭.豚鼠圆窗膜破裂引起耳蜗形态变化的探讨[J].听力学及言语疾病杂志,2004,12(4):254-255,T002. |
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| 作者姓名： | 刘秀丽 别旭 |
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| 作者单位： | 1. 大连医科大学附属第一医院耳鼻咽喉科,大连,116011
2. 大连医科大学附属第二医院耳鼻咽喉科 |
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| 摘 要： | 目的探讨外淋巴瘘时耳蜗形态学变化。方法选用10只(10耳)豚鼠，刺破圆窗膜致使外淋巴液漏出，4小时后进行耳蜗组织形态学观察。结果发现膜迷路水肿2耳(2／10)；1耳出现血管纹剥离、耳蜗内静脉淤血、耳蜗内出血；7耳(7／10)没有明显异常变化。结论圆窗膜破裂可导致部分耳蜗组织形态学异常。
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| 关 键 词： | 外淋巴瘘 耳蜗 组织学观察 豚鼠 |
| 文章编号： | 1006-7299(2004)04-0254-02 |
| 修稿时间： | 2003年8月22日 |
Effects of Round Window Membrane Rupture on Morphological Changes of Guinea Pig's Cochlea |
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| Abstract: | Objective Clinical reports on perilymphatic fistulae(PLF) of the round window membrane(RWM) have shown different degrees of hearing loss. For the unknown mechanisms of hearing loss, the morphological changes of cochlea with perilymphatic fistulae(PLF) was studied.Methods Among 10 guinea pigs, each ear on one side was punctured and the ear of another side was used as control. 4 hours after operation, the morphological changes of cochlea were observed.Results It was found that 2 ears with endolymphatic hydrops, 1 ear with strica vascularis stripped, venous hyperemia and hemorrhage in cochlea, 7 ears with no changes.Conclusion The study suggestes that the normal and the abnormal morphological changes of cochlea can all be seen after the rupture of RWM. |
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| Keywords: | Perilymphatic fistula Cochlea Morphological Guinea pig |
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