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| 灵五颗粒利胆作用的实验研究 | |
| 引用本文： | 徐雪钰,魏萍,于珊,李建宇,黄正明. 灵五颗粒利胆作用的实验研究[J]. 解放军药学学报, 2011, 27(4): 328-330. DOI: 10.3969/j.issn.1008-9926.2011.04.014 |
| 作者姓名： | 徐雪钰 魏萍 于珊 李建宇 黄正明 |
| 作者单位： | 1. 解放军309医院药剂科, 北京,100091 2. 总后勤部卫生部药品仪器检验所, 北京,100071 3. 解放军302医院药学部, 北京,100039 |
| 基金项目： | 医院制剂基金项目,No.201002-03 |
| 摘 要： | 目的 实验观察灵五颗粒对健康Wistar大鼠的利胆效果.方法 40只Wistar大鼠随机分为生理氯化钠溶液组、阳性药熊去氧胆酸对照(0.63 g/kg)组、灵五颗粒低、中、高(1.75、3.5、7.0 g/kg)剂量组,每组8只.麻醉状态下手术暴露胆总管,插入导管,引流胆汁,给药前30 min收集记录各组胆汁流量.采用... |
| 关 键 词： | 灵五颗粒 利胆作用 胆汁成分 |
Studies on Cholaneresis Effects of Lingwu Granules on Rats |
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| XU Xue-yu,WEI Ping,YU Shan,LI Jian-yu,HUANG Zheng-ming. Studies on Cholaneresis Effects of Lingwu Granules on Rats[J]. Pharmaceutical Journal of Chinese People's Liberation Army, 2011, 27(4): 328-330. DOI: 10.3969/j.issn.1008-9926.2011.04.014 | |
| Authors: | XU Xue-yu WEI Ping YU Shan LI Jian-yu HUANG Zheng-ming |
| Affiliation: | ③①Department of Pharmacy,Hospital 309 of PLA,Beijing100091,China;②Institute for Drug and Instrument Control of Health Dept GLD of PLA,Beijing100071,China;③Department of Pharmacy,Hospital 302 of PLA,Beijing100039,China |
| Abstract: | Objective To investigate the cholaneresis effect of Lingwu Granules on healthy Wistar rats.Methods A total of 40 Wistar rats were randomly divided into five groups: saline group,ursodeoxycholic acid group and Lingwu Granules treatment groups(1.75,3.5,7.0 g/kg).There were eight rats in each group.Choledochus was exposed under anesthesia before a canal was inserted to drain the bile.The volume of the bile was measured 30 min before treatment.Drugs were administrated through duodenum and the bile volume was me... |
| Keywords: | Lingwu Granules cholaneresis effects bile chemical component |
| 本文献已被 CNKI 维普 万方数据 等数据库收录！ | |
