生物组织光散射等效颗粒模型及Mie相函数计算

为研究生物组织的散射特性,将其从散射效果上等效为离散的球形散射体的集合,结合经典的Mie散射理论对生物组织散射相函数进行数值计算。计算结果表明:Mie散射相函数能够描述生物组织后向(大角度)散射光强振荡特性与等效粒径的对应关系,可为基于后向散射光的无创伤或微创伤诊疗提供理论依据;Mie散射相函数能够解释生物组织散射光空间分布与波长的相关性,为医学诊疗上入射光波长选择提供参考;合理选择集群散射体粒度分布参数,可实现对复杂生物组织散射相函数的精确描述。

Equivalent Particle' s Model of Biological Tissue and Calculation of Mie Phase Function

The discrete equivalent spherical scatterers aggregate model is developed for investigating the scattering characteristic of biological tissue. Combined with classic Mie theory, the phase function is calculated. The numerical results show that Mie phase function can not only describe the relationship between the equivalent diameter and the light intensity oscillation in backscattering region, which provides a theory tool of noninvasive or minimally invasive diagnosis and treat; but also interpret the dependency of scattering light intensity distribution on light wavelength, which supplies references to select incident light wavelength in practice. With proper parameters of particle size distribution, Mie phase function can characterize complex biological tissue.