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CircTLK1 modulates sepsis-induced cardiomyocyte apoptosis via enhancing PARP1/HMGB1 axis–mediated mitochondrial DNA damage by sponging miR-17-5p |
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| Authors: | Yu Qiu Ying Yu Xiao-Mei Qin Tao Jiang Yan-Fang Tan Wen-Xian Ouyang Zheng-Hui Xiao Shuang-Jie Li |
| Affiliation: | 1. Emergency Center, Hunan Children’s Hospital, Changsha, China
Contribution: Conceptualization (equal), Funding acquisition (equal), Methodology (equal), Writing - original draft (equal);2. Department of Hepatopathy, Hunan Children’s Hospital, Changsha, China Contribution: Data curation (equal), Formal analysis (equal), Validation (equal);3. Department of Hepatopathy, Hunan Children’s Hospital, Changsha, China Contribution: Data curation (equal), Formal analysis (equal), ?Investigation (equal);4. Department of Hepatopathy, Hunan Children’s Hospital, Changsha, China Contribution: Formal analysis (equal), ?Investigation (equal), Validation (equal), Visualization (equal);5. Department of Hepatopathy, Hunan Children’s Hospital, Changsha, China Contribution: ?Investigation (equal), Methodology (equal), Resources (equal), Writing - original draft (equal);6. Department of Hepatopathy, Hunan Children’s Hospital, Changsha, China Contribution: Formal analysis (equal), Software (equal), Visualization (equal), Writing - original draft (equal);7. Emergency Center, Hunan Children’s Hospital, Changsha, China;8. Department of Hepatopathy, Hunan Children’s Hospital, Changsha, China |
| Abstract: | |
| Keywords: | apoptosis circTLK1/miR-17-5p/PARP1/HMGB1 axis mitochondrial dysfunction mtDNA oxidative damage septic cardiomyopathy |
