静电纺丝纤维支架在软骨组织重建中的设计应用 |
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引用本文: | 王春晖,贺娇娇,王思涵,郭小凯,赵明璨,刘畅. 静电纺丝纤维支架在软骨组织重建中的设计应用[J]. 海南医学, 2016, 0(19): 3197-3199. DOI: 10.3969/j.issn.1003-6350.2016.19.034 |
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作者姓名: | 王春晖 贺娇娇 王思涵 郭小凯 赵明璨 刘畅 |
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作者单位: | 吉林大学口腔医院正畸科,吉林 长春,130021 |
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摘 要: | 软骨损伤是临床常见疾病之一。软骨是一种无神经和血管营养的组织,其自身修复能力很差。组织工程学为解决这一难题提供了新方法。组织工程学主要由支架材料、种子细胞和生长因子三要素构成。而其中支架材料是近年来组织工程学研究的热点。静电纺丝技术更是由于其能形成多孔隙的纳米纤维支架而备受青睐。本文具体介绍静电纺丝技术在软骨组织工程学中的设计应用。
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关 键 词: | 组织工程 支架材料 静电纺丝 软骨 |
Application of electrospinning technology in the cartilage tissue engineering |
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Abstract: | Cartilage injury is one of clinical common diseases. Since cartilage is a kind of tissue without nerves and blood vessels, its self-repair ability is limited. Tissue engineering provides an approach to solve this problem. Tissue engineering is mainly composed of scaffolds, seeding cells and growth factors. And the scaffold material is a hot spot in the research of tissue engineering in recent years. Electrospinning can produce polymer fibers with diameters down to nanoscale dimensions and form high porosity non-woven mat. This paper introduces the application of electrospinning technology in the cartilage tissue engineering. |
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Keywords: | Tissue engineering Scaffolds Electrospinning Cartilage |
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