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龙津对体外血栓形成、凝血及纤维蛋白溶解作用的实验研究
引用本文:金惠铭,曹翔,张国平,钱睿哲,杨诗春,龚之森,邱少中.龙津对体外血栓形成、凝血及纤维蛋白溶解作用的实验研究[J].中国微循环,1996(2).
作者姓名:金惠铭  曹翔  张国平  钱睿哲  杨诗春  龚之森  邱少中
作者单位:上海医科大学病理生理学教研室!200032(金惠铭,曹翔,张国平,钱睿哲,杨诗春),南京市金宁信息技术研究所(龚之森,邱少中)
摘    要:在正常和DIC家兔或大鼠中证明,口服龙津后,体外血栓长度缩短,血栓重量减轻,全血凝块和纤维蛋白凝块溶解加速,KPTT延长,ELT缩短,t-PA活性增强(P<0.05)。以上资料提示龙津有抗凝和溶栓的双重作用。

关 键 词:龙津  血栓  抗凝  溶栓

An Experimental Study on Effects of Longjin on Thrombosis, Coagulation and Fibrinolysis in Vitro
Jin Huiming,Cao Xiang,Zhang Guoping,et al Dept. of Pathophysiology Shanghai Medical University,Shanghai..An Experimental Study on Effects of Longjin on Thrombosis, Coagulation and Fibrinolysis in Vitro[J].Journal of Chinese Microcirculation,1996(2).
Authors:Jin Huiming  Cao Xiang  Zhang Guoping  Dept of Pathophysiology Shanghai Medical University  Shanghai
Abstract:Longjin is a preparation of earthworm. To study its effects on coagulation and fibrinolysis in vitro, normal and DIG rabbits and rats were adopted. The results are as follows: after administration of Longjin orally the length and the weight of thrombus was reduced. the hemolysis of whole blood clot and fibrin clot was accelerated, the KPTT was prolonged, the ELT was shortened and the activity of t-PA was increased significantly (P<0. 05). The data mentioned above suggest that Longjin plays a dual role of anticoag-ulation and thrombolysis.
Keywords:Longjin thrombosis anticoagulation thrombolysis
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