| 用Jones试剂合成医药中间体4-乙酰氨基环己酮 |
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| 引用本文： | 刘琴,尹先清.用Jones试剂合成医药中间体4-乙酰氨基环己酮[J].化学与生物工程,2006,23(5):15-16. |
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| 作者姓名： | 刘琴 尹先清 |
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| 作者单位： | 长江大学化学与环境工程学院,湖北,荆州,434023 |
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| 摘 要： | 以4-乙酰氨基环己醇为原料、Jones试剂作氧化剂合成了医药中间体4-乙酰氨基环己酮,反应条件温和、易于控制,反应时间大大缩短,收率稳定,效果令人满意.
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| 关 键 词： | Jones试剂 氧化反应 4-乙酰氨基环己酮 |
| 文章编号： | 1672-5425（2006）05-0015-02 |
| 收稿时间： | 2006-02-22 |
| 修稿时间： | 2006年2月22日 |
Synthesis of the Medicinal Intermediate N-(4-Oxocyclohexyl) Acetamid with Jones Reagent |
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| LIU Qin,YIN Xian-qing.Synthesis of the Medicinal Intermediate N-(4-Oxocyclohexyl) Acetamid with Jones Reagent[J].Chemistry & Bioengineering,2006,23(5):15-16. |
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| Authors: | LIU Qin YIN Xian-qing |
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| Abstract: | Using Jones reagent as oxidant and 4-acetamidocyclohexanol as raw material,the medicinal intermediate N-(4-oxocyclohexyl) acetamid was synthesized.The experimental results showed:the reaction conditions were mild and controllable,the reaction time was shortened greatly while the yield was stable.Jones reagent was proved to be a satisfactory oxidant for the synthetic reaction. |
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| Keywords: | Jones reagent oxidize reaction N-(4-oxocyclohexyl) acetamid |
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