| 肺鳞癌驱动基因及其靶向治疗的研究进展 |
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| 引用本文： | 黄 芳,李 颖,姜 达. 肺鳞癌驱动基因及其靶向治疗的研究进展[J]. 肿瘤学杂志, 2014, 20(12): 1035-1039 |
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| 作者姓名： | 黄 芳 李 颖 姜 达 |
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| 作者单位： | 河北医科大学第四医院;河北医科大学第四医院;河北医科大学第四医院 |
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| 摘 要： | 应用分子靶向药物治疗晚期肺腺癌已逐渐成为当今临床研究的主流,其中EGFR基因突变患者可从靶向治疗中获益。肺鳞癌驱动基因的研究相对较少,近期多种检测技术对肺鳞癌标本进行基因检测,结果发现多数标本存在多个可测靶点,针对这些靶点已开发出一系列药物,其疗效仍待观察。
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| 关 键 词： | 肺肿瘤 鳞状细胞 驱动基因 靶向治疗 |
| 收稿时间： | 2014-02-12 |
Progress in Lung Squamous Carcinoma Drive Gene and Its Targeted Therapy |
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| HUANG Fang,LI Ying,JIANG Da. Progress in Lung Squamous Carcinoma Drive Gene and Its Targeted Therapy[J]. Journal of Chinese Oncology, 2014, 20(12): 1035-1039 |
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| Authors: | HUANG Fang LI Ying JIANG Da |
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| Affiliation: | The Fourth Hospital of Hebei Medical University |
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| Abstract: | Application of targeted therapy for advanced lung adenocarcinoma has gradually be- come the mainstream of the clinical research nowadays. Patients with EGFR mutation can bene- fit from it. Lung squamous carcinoma drive gene is relatively studied few. A variety of testing techniques for genetic testing lung squamous carcinoma specimens find that most of the speci- mens exist measurable targets. According to these targets it has developed a series of therapeu- tic drugs. However the effectiveness remains to be defined. |
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| Keywords: | lung neoplasms squamous cell drive gene targeted therapy |
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