卵磷脂及复合物的功能活性研究进展

卵磷脂即磷酸基团的磷脂酰胆碱,是生物膜的基本成分。卵磷脂复合物指磷脂分子和活性成分通过电荷迁移作用形成的较为稳定的化合物或络合物,它可使活性分子的理化性质发生改变,提高其生物利用度。卵磷脂来源广泛,卵磷脂复合物制备方法简单,近年来在药物制剂方面特别是在中西药卵磷脂复合物应用研究逐渐增多,并取得了较大的成果。该文对卵磷脂与活性成分的复合机理及卵磷脂复合物的种类和功能活性进行概述。

Research progress on the functional activity of lecithin and lecithin complex

Lecithin,the phosphatidylcholine of the phosphate group,is the basic component of biological membranes.Lecithin complexes are relatively stable compounds or complexes formed by phospholipid molecules and active ingredients through charge-transfer interaction.The physical and chemical properties of active ingredients change and bioavailability are improved.There are many resources of lecithin,and the preparation of lecithin complex is simple.In recent years,researches on pharmaceutical preparations have gradually increased,especially in the application of Chinese and Western medicine lecithin complexes,and good results have been obtained.This article summarized the compounding mechanism of lecithin and active ingredients,the types and functional activities of lecithin complexes.