14例大疱性表皮坏死松解型药疹治疗体会

报告14例大疱性表皮坏死松解型药疹的治疗。以磺胺类药和解热镇痛药引起者居多,各4例。皮损面积按九分法计算,皮损面积80％以上者9例,80％以上者5例,治愈9例,死亡5例,我们认为早期使用足够剂量皮质激素类药物是有效措施。病程中注意防治感染,给予足够的液体以防止水电解质失平衡,局部治疗使用本院中药“五黄油”。

Treatment of 14 Patients with Epidermolysis Bullosa Drug Eruption

Treatment of tourteen patients with epidermolusis bullosa drug erupion has been reported. The major causes were sulfonamides and antipyretic analegesics,each of which involved 4 patients. According to the "The rule of nines" method used in burn patient to evaluate the cutaneous lesion,over 80% of the surface area in 9 patients and under 80% in 5 patients were encountered. Among the 14 patients, 9 were cured and 5 died. The results suggest that emphasis should be placed on early treatment by enough dosage of cortical hormone ,control of infection ,enogh fluid transfusion to keep the patients from water-electrolyte unbalance and local application of Chinese traditional herb pharmaceutics"Wu Huang You".