| 人参芦头抗心律失常活性成分研究 |
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| 引用本文： | 张永鹤,林景南,裴玉萍,刘崇铭,徐绥绪,姚新生,荻原幸夫,竹田忠紘.人参芦头抗心律失常活性成分研究[J].沈阳药科大学学报,1992(2). |
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| 作者姓名： | 张永鹤 林景南 裴玉萍 刘崇铭 徐绥绪 姚新生 荻原幸夫 竹田忠紘 |
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| 作者单位： | 沈阳药学院，沈阳药学院，沈阳药学院，沈阳药学院，沈阳药学院，沈阳药学院，名古屋市立大学，名古屋市立大学 |
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| 摘 要： | 从人参(Panax ginseng C.A.Meyer)芦头中分离得到10个化合物。经理化性质、波谱分析和薄层析分别鉴定为:20(R)-人参皂甙-Rh_1(Ⅰ),人参皂甙-Rg_3(Ⅱ),20(S)-人参皂甙-Rg_2(Ⅲ),-Rg_1(Ⅳ),-B(Ⅴ),-Rd(Ⅵ),-Rc(Ⅶ),-Rb_2(Ⅷ),-Rb_1(Ⅸ),-Ro(Ⅹ).其中化合物Ⅰ,Ⅱ为首次从人参芦头中分离得到的已知成分,并对其中9种主要人参皂甙进行了抗氯化钡诱发大白鼠心律失常作用的研究。
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| 关 键 词： | 人参 人参皂甙 抗心律失常 |
STUDIES ON THE ANTIARRHYTHMIC CONSTITUENTS FROM THE RHIZOMES OF PANAX GINSENG C.A.MEYER |
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| Zhang Yonghe Lin Jingnan Pei Yuping Chen Yingjie Liu Chongming Xu Shuixu Yao Xinsheng Shenyang Coll. of Pharm. Ogihara Yukie Takeda Tadahiro Nagoya City Univ..STUDIES ON THE ANTIARRHYTHMIC CONSTITUENTS FROM THE RHIZOMES OF PANAX GINSENG C.A.MEYER[J].Journal of Shenyang Pharmaceutical University,1992(2). |
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| Authors: | Zhang Yonghe Lin Jingnan Pei Yuping Chen Yingjie Liu Chongming Xu Shuixu Yao Xinsheng Shenyang Coll of Pharm Ogihara Yukie Takeda Tadahiro Nagoya City Univ |
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| Affiliation: | Zhang Yonghe Lin Jingnan Pei Yuping Chen Yingjie Liu Chongming Xu Shuixu Yao Xinsheng Shenyang Coll. of Pharm. Ogihara Yukie Takeda Tadahiro Nagoya City Univ. |
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| Abstract: | Ten compounds were isolated from the rhizomes of Panax ginseng C.A. Meyer and identified as 20(R)-ginsenoside-Rh_1 (1), ginsenoside-Rg_3(2),-Rg_2(3), -Rg_1(4), -B(5), -Rd(6), -Rc(7), -Rb_2(8), -Rb(9) and -Ro (10). The compounds(1) and (2) were for the first time isolated from the rhizomes of the title plant. Nine of the ten ginsenosides obtained were shown to have antiarrhythmic activity. |
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| Keywords: | Panax Ginseng C A Meyer Ginsenosides Antiarrhythmic activity |
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