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老年2型糖尿病患者体质量指数和腰臀比与血小板参数的相关性研究
引用本文:刘倩,姜春艳,王玲,张沫,孟东,于德民. 老年2型糖尿病患者体质量指数和腰臀比与血小板参数的相关性研究[J]. 重庆医学, 2015, 0(30). DOI: 10.3969/j.issn.1671-8348.2015.30.001
作者姓名:刘倩  姜春艳  王玲  张沫  孟东  于德民
作者单位:1. 天津医科大学代谢病医院/内分泌研究所/卫生与计划生育委员会激素与发育重点实验室 肥胖代谢科 300070;2. 天津医科大学代谢病医院/内分泌研究所/卫生与计划生育委员会激素与发育重点实验室 检验科 300070;3. 天津医科大学代谢病医院/内分泌研究所/卫生与计划生育委员会激素与发育重点实验室 内分泌科 300070
基金项目:国家自然科学基金资助项目
摘    要:目的:研究老年2型糖尿病患者体质量指数(BMI)和腰臀比(WHR)与血小板参数的相关性。方法选取2012年10月到2014年2月该院收治的82例2型糖尿病患者作为研究对象,选取同期进行健康体检的80例健康老年人作为对照组。将患者按照BM I分为3组,Ⅰ组(正常组)23例,Ⅱ组(超质量组)38例,Ⅲ组(肥胖组)21例。比较各组患者和对照组的血糖、糖化血红蛋白(HbA1c)水平、血脂异常和腹型肥胖的发生率;比较不同BMI和WHR的老年人血脂水平和血小板参数,比较不同血脂水平老年人的血小板参数。结果3组患者的血糖、HbA1c水平、BMI、WHR、血脂异常和腹型肥胖的发生率高于对照组,差异有统计学意义(P<0.05)。不同BMI和WHR老年人的血脂水平和血小板参数差异有统计学意义(P<0.05)。不同血脂水平老年人的血小板参数差异有统计学意义(P<0.05)。结论老年2型糖尿病患者BMI和WHR与血小板参数具有一定的相关性,可能与肥胖和血脂代谢紊乱对血管内皮的损伤有关。

关 键 词:糖尿病 ,2型  体质量指数  腰臀比  血小板参数

The relevance between body mass index and waist-to-hipratio with platelet parameters in gerontol patients with type 2 diabetes mellitus
Abstract:Objective To study the relevance between body mass index and waist‐to‐hipratio with platelet parameters in ger‐ontol patients with type 2 diabetes mellitus .Methods From October 2012 to February 2014 ,82 gerontol patients with type 2 diabe‐tes mellitus were chosen as objectives ,all patients were divided into 3 groups according to BMI:23 patients in group Ⅰ ,38 patients in group Ⅱ ,and 21 patients in group Ⅲ ;at same period ,80 healthy old people were chosen as control group .The blood glucose he HbA1c level ,the rate of dyslipidemia and rate of abdominal obesity ,BMI and WHR were compared among different group .The blood lipid level and platelet parameters among all the 162 old people with different BMI and WHR were compared .The platelet pa‐rameters among old people with different blood lipid level were compared .Results The blood glucose he HbA1c level ,BMI ,WHR and the rate of dyslipidemia and rate of abdominal obesity were higher ,the difference had statistical significance(P< 0 .05) .The blood lipid level and platelet parameters among old people with different BMI or WHR had statistical difference(P< 0 .05) .The difference of platelet among old people with different blood lipid level had statistical significance(P<0 .05) .Conclusion In gerontol patients with type 2 diabetes mellitus ,body mass index and waist‐to‐hipratio have relevance with platelet parameters ,which is rela‐tive to the damage of obesity and high blood lipid on blood vessel endothelium .
Keywords:diabetes mellitus,type 2  body mass index  waist-to-hipratio  platelet parameters
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