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Detection of a C-insertion polymorphism within the human tumor necrosis factor alpha (TNFA) gene |
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| Authors: | Brigitta M. N. Brinkman Eric L. Kaijzel Tom W. J. Huizinga Marius J. Giphart Ferdinand C. Breedveld Cornelis L. Verweij |
| Affiliation: | (1) Department of Rheumatology, University Hospital Leiden, Building 1, PO box 9600, NL-2300 RC Leiden, The Netherlands;(2) Department of Immunohematology and Blood Bank, University Hospital Leiden, Leiden, The Netherlands |
| Abstract: | We have identified a C-insertion polymorphism in the 5'UTR of the first exon of the human tumor necrosis factor alpha (TNFA) gene. TNFA is a cytokine that plays an important role in the inflammatory response. |
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