| 超氧自由基(O_2~■)水平在儿童急性肾小球肾炎及其治愈后的变化 |
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| 引用本文： | 孔祥蓁,朱晓明,毕红,王燕萍. 超氧自由基(O_2~■)水平在儿童急性肾小球肾炎及其治愈后的变化[J]. 西安交通大学学报(医学版), 1993, 0(3) |
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| 作者姓名： | 孔祥蓁 朱晓明 毕红 王燕萍 |
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| 作者单位： | 西安医科大学机能实验中心，陕西师范大学医院，西安医科大学生化教研室，西安医科大学机能实验中心 西安 710061，西安 710061 |
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| 摘 要： | 以超氧化物歧化酶(SOD)作为分子探针测定了儿童急性肾小球肾炎(AGN)急性期红细胞内超氧阴离子自由基(O_2~?)含量及其治愈后的变化。结果表明,病儿与正常对照者的O_2~?水平有非常显著的差异;急性期与治愈后的差异也非常显著。提示超氧阴离子自由基在AGN发病中有重要作用。
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| 关 键 词： | 急性肾小球肾炎 超氧阴离子自由基 超氧化物歧化酶 V_C V_E 辅酶Q_(10) |
THE CHANGE OF SUPEROXIDE ANION RADICAL CONCENTRATION IN ACUTE PHAGE AND RECOVER OF ACUTE GLOMERULONEPHRITIS IN CHILDREN |
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| Kong Xiangzhen,Zhu Xiaoming,Bi Hong,et al Functional Experimental Centre. THE CHANGE OF SUPEROXIDE ANION RADICAL CONCENTRATION IN ACUTE PHAGE AND RECOVER OF ACUTE GLOMERULONEPHRITIS IN CHILDREN[J]. Journal of Xi‘an Jiaotong University:Medical Sciences, 1993, 0(3) |
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| Authors: | Kong Xiangzhen Zhu Xiaoming Bi Hong et al Functional Experimental Centre |
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| Abstract: | In this paper, the change of superoxide anionradical concentration in erythrocytes was measuredby using SOD as a molecular probe, during acutephage and recover of acute glomerulonephritis(AGN) in children. The result showed that therewas very significant difference in O_2 concentrationbetween the patient group and control group) aswell as between acute phage and recover stage. Itsuggests that increased level of superoxide anionradical plays an important role in the pathogene-sis. |
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| Keywords: | acute glomerulonephritis (AGN ) superoxide anion radical superoxide dismutase (SOD) V_C V_E coenzyme Q_(10) |
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