高海拔地区围产儿死亡中出生缺陷的顺位分析

通过我院１９８８年１月～１９９３年１２月围产儿死亡中出生缺陷的临床病理分析及顺位，探讨高海拔地区（西宁海拔２２６０ｍ）围产儿死亡中的出生缺陷的特点，本组围产儿死亡率２０‰，共１０３例，其中发现有出生缺陷者２７例，主要为严重的心血管畸形，多数伴有多发畸形，其次为神经系统开放性畸形，消化系统畸形等，分析提示，出生缺陷以心血管畸形为主，明显不同平原地区，可能与高海拔寒冷，病毒感染频繁，缺氧等因素有关。

CIS-POSITION ANALYSIS OF CONGENITAL DEFECTS OF PERINATAL DEATH IN HIGH ALTITUDE

n the basis of clinical pathological and cis-position analysis of congenital defects of perina-tal deaty in our hospital from Jan. 1988 to Dec. 1993 the characteristics of congenital defects of perinatal death in high aItitude(Xining,2 260m)were discussed.Among the l03cases in thisstudy the death ratio was 20%, the congenital defects were found in 27 cases which constituted26.2%. The mortality of congenital defects was 52.4/10 000,the main death causes were seriouscardiovascular defects,open deformity of nervous system and alimentary tract deformity. It wasfound that the cardiovascular deformity as main death cause was obviously different from plainregion and it may berelated to cold,frequent virus infection and hypoxia in high altitude.