| 精液与血液PGM_1亚型相关性和男性不育症与PGM_1亚型的相关性 |
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| 引用本文： | 伍新尧,蔡珊元,吴国华.精液与血液PGM_1亚型相关性和男性不育症与PGM_1亚型的相关性[J].中山大学学报(医学科学版),1990(3). |
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| 作者姓名： | 伍新尧 蔡珊元 吴国华 |
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| 作者单位： | 中山医科大学法医学系
(伍新尧)，中山医科大学附属第一医院妇产科
(蔡珊元)，中山医科大学附属第一医院妇产科(吴国华) |
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| 摘 要： | 用等电聚焦电泳技术测定98例精液/血液标本对葡萄糖磷酸变位酶(phosphoglucomutase,简称PGM_1)亚型的结果,证明同一男性个体血液和精液的PGM_1表型完全一致。同时,测定了171例男性不育症患者的PGM_1亚型。其结果与广州地区正常人群组的比较后,可见男性不育症组的PGM_11~-,1~-2~-,2~-三型的频率较正常人群高,具有显著性意义。在精子数低于0.4亿/ml的患者中,这3型的频率更高。14例无精子精液同样可以测出其PGM_1亚型,说明精液中的PGM_1酶活性,除精子外,还有其他来源。
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| 关 键 词： | 精液 血液 PGM_1 亚型 男性不育症 |
EXAMINATION OF THE CORRELATION OF PGM, SUBTYPING IN BLOOD AND SEMEN, AND OF MALE INFERTILITY AND PHENOTYPES |
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| Wu Xinyao.EXAMINATION OF THE CORRELATION OF PGM, SUBTYPING IN BLOOD AND SEMEN, AND OF MALE INFERTILITY AND PHENOTYPES[J].Journal of Sun Yatsen University(Medical Sciences),1990(3). |
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| Authors: | Wu Xinyao |
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| Abstract: | The results of PGM, subtyping of 93 blood-semen pairs using IEF were presented. It showed that the phenotypes of blood and semen in the same male were identical. Meanwhile, the phenotypes of 171 male patients of infertility were determined, the results were as follows: PGM, 1- 47(27.49%), IT 21(12.28%), 1- 8(4.63%),1+ 2+ 34 (19.88%), 1+2-31(18.18%), 1~2+ 3(1.75%), 1-2- 7(4.09%), 2+7 (4.09%), 2+ 2- 5(2.92%), 2- 4(2.34%), T 8 2(1.17%), 2 + 8 1(0.58%). The frequencies of PGM, 1-, 1-2-, and 2- phenotypes of the male infertility patients were higher statistically than that of the healthy person group. All of 14 semens of azoospermia could be detected for PGM, subtype, combining the result that the semen plasma could be subtyped for PGM,, it suggested that there was other resource of seminal PGM, activity besides spermatozoa. |
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| Keywords: | Semen Blood PGM subtype Male infertility |
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