嘉善县人群普查检出的21例结直肠癌临床病理分析

我们首次采用数学模式调查表、反向被动血凝法和纤维乙状结肠镜程序方案,在嘉善县进行结直肠癌普查,共查出结直肠癌21例。与同期在医院诊治的结直肠癌进行比较。结果发现,普查组在肿瘤大小、大体类型、组织学类型、浸润深度和 Dukes 分期均显著地不同于临床组(P<0.05,或 P<0.01)。普查组中肿瘤≤2 cm者达28.6%,高分化管状腺癌占57.1%,Dukes A 期占47.6%;而临床组绝大多数肿瘤>2 cm 者占96%,中分化管状腺癌占50.7%,Dukes A 期仅占14.7%。提示在结直肠癌高发地区实施上述普查方案,有可能发现更多的体积小,分化程度高,侵袭局限的早期癌。

Clinical pathological analysis of 21 cases of colorectal cancer detected in mass screening in Jiashan county

Jiashan county is one of the highest mortality regions of colorectal cancer in our country. The article reports the detection of 21 cases of colorectal cancer in Jiashan county in a mass screening(3162 subjects)by means of the sequence progrom consisting of questionnaire,reverse passive hemagglutination(RPHA)and 60 cm fiberoptic colonoscopy to find 28.6% cases of tumor with the size<2cm,57.1% of high differential adenocarcinoma and 47.6% at Dukes stage A in the screening group(21 colorectal cancers),while the clinical group witnessed(75 colorectal cancers) 96% of cases with their tumor size>2cm,80.7% of mediated differential adenocarcinoma and 14.7% at Dukes stage A.The differences between both groups had statistical significance(P<0.05). The results indicate the possibility of detection of early staged colorectal cancers with small size of high differentiation and regional invasion through the implementation of above mentioned sequence screening program in high morbidity regions of colorectal cancer.