| 托吡酯长期治疗儿童癫痫的临床研究 |
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| 引用本文： | 景学医. 托吡酯长期治疗儿童癫痫的临床研究[J]. 实用诊断与治疗杂志, 2003, 17(1): 17-17 |
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| 作者姓名： | 景学医 |
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| 作者单位： | 450003,郑州市,河南省人民医院 |
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| 摘 要： | 目的 :观察托吡酯长期治疗儿童各型癫痫的疗效和安全性。方法 :对应用托吡酯 (添加或单药 )治疗 5个月发作减少≥ 75 %的 3 1例患者继续追踪巩固治疗 >2a ,并观察疗效维持和不良反应。结果 :3 1例各型癫痫患儿经应用托吡酯治疗 >2a ,疗效比较稳定 ,复发 6例 (19 4% ) ,不良反应 10例 ,除少汗不良反应外未见血液、肝、肾等重要脏器损害。不良反应均在 5个月内消失。结论 :托吡酯是一种广谱、高效、安全性好的新型抗癫痫药
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| 关 键 词： | 托吡酯 癫痫 |
| 文章编号： | 1006-7566(2003)01-017-02 |
| 修稿时间： | 2002-10-09 |
Clinical study on Topiramate in the long-term treatment of epilepsy in children |
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| JING Xueyi.Henan Provincial People's Hospital,Zhengzhou ,China. Clinical study on Topiramate in the long-term treatment of epilepsy in children[J]. Journal of Practical Diagnosis and Therapy, 2003, 17(1): 17-17 |
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| Authors: | JING Xueyi.Henan Provincial People's Hospital Zhengzhou China |
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| Affiliation: | JING Xueyi.Henan Provincial People's Hospital,Zhengzhou 450003,China |
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| Abstract: | Objective To observe the effect and safety of Topiramate in the long-term treatment of various pediatric epilepsy.Methods Thirty-one patients were continuously treated with Topiramate for over 2 years to observe its stability of therapeutic effect and adverse reaction after 5-month-treatment when attack times were reduced by 75%.Results Six patients(19.4%) recurred.Ten had adverse reactions which disappared within 5 months except less sweat.Topiramate did not influence hepatic,renal function and blood system parameters.Conclusion Being a new agent of antiepileptic drugs,Topiramate is safe and effective. |
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| Keywords: | Topiramate epilepsy |
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