肌萎缩性侧索硬化症的诊断分析

目的 总结肌萎缩性侧索硬化症(ALS)的临床特点.方法 对49例ALS患者的临床资料进行回顾性分析.结果 ALS平均发病年龄为49.0岁;男女比例为2.1:1;肌无力、肌肉萎缩是其最早和最常见症状;其中发生在单侧上肢者24例,双上肢者3例,单侧下肢者9例,双下肢者3例,偏侧1例,双上、下肢1例,球部8例.肌电图与MRI对诊断有重要意义;49例中误诊46例,误诊率为93.9%.结论 ALS多为中年发病,男性多于女性,肌电图和MRI对诊断和鉴别诊断有重要意义.

Diagnostic study of amyotrophic lateral sclerosis cases

Objective To study the clinical features of ALS in order to increase the awareness of ALS. Methods Clinical data of 49 cases with ALS were analyzed retrospectively. Results The mean age at onset was 49.0. Sex ratio (male/female) was 2.1:1. Weakness and awkwardness in one hand or arm were probably the earliest and commonest symptoms. EMG had significant value in diagnosis and MRI was beneficial in the differential diagnosis. The rate of misdiagnosis was very high. The most common misdiagnosis was cervical spondylotic myelopathy. Conclusions ALS is an age-related?male predominant disease. Both EMG and MRI have important value in diagnosis and differential diagnosis of ALS.