脑钠肽在心脏外科手术中的作用

目的 探讨脑钠肽(BNP)对心脏外科手术患者预后的影响.方法 选择首次行心脏外科手术患者115例,进行术前BNP测定,观察BNP与术后发生心房颤动、呼吸机使用时间、住院时间及术后30 d病死率等情况的关系.结果 患者是否有高血压、糖尿病、心肌梗死病史,是否存在左主干病变及血红蛋白水平与BNP指标无明确的相关性(P>0.05).欧洲心脏手术风险评估系统评分(5±3)分],与BNP水平明显相关(P=0.003),BNP与左室射血分数有相关性(P=0.002).术后呼吸机使用时间(15.0±5.4)h,住院时间(32±11)d,与BNP有明确的相关性(P=0.035、0.001),但与术后纵隔感染、心房颤动及术后30 d病死率之间的关系不确切(P>0.05).结论 BNP可以用于心脏外科手术后风险的预测.

Abstract：

Objective To investigate the influence of brain natrluretic peptide(BNP) in the prognosis of cardiac surgery.Methods Selected 115 cases of pafients with the first cardiac surgery.Their BNP concentration was measured before operation. Observed the relationship between BNP and postoperative atrial fibrillation,mechanical ventilation time,hospital stay,and the mortality of 30 d.Results Whether the patients had hypertension,diabetes,myocardial infarction history,left main stem disease and hemoglobin level or not,showed no definite relationship with BNP (P>0.05).Preoperative lower left ventricular ejection fraction (LVEF)(P=0.002) and European system for cardiac operation risk evaluation (5±3)scores](P=0.003) were associated with higher BNP level.Postoperative mechanical ventilation time was(15.0±5.4)h,hospital stay was (32±11) d,showed a clear relationship with BNP(P= 0.035,0.001),but postoperative mediastinal infection,atrial fibrillation and mortality of 30 d had no definite relationship with BNP(P>0.05).Conclusion BNP can be used to predict the risk after cardiac surgery.

The role of brain natriuretic peptide in cardiac surgery

Objective To investigate the influence of brain natrluretic peptide(BNP) in the prognosis of cardiac surgery.Methods Selected 115 cases of pafients with the first cardiac surgery.Their BNP concentration was measured before operation. Observed the relationship between BNP and postoperative atrial fibrillation,mechanical ventilation time,hospital stay,and the mortality of 30 d.Results Whether the patients had hypertension,diabetes,myocardial infarction history,left main stem disease and hemoglobin level or not,showed no definite relationship with BNP (P>0.05).Preoperative lower left ventricular ejection fraction (LVEF)(P=0.002) and European system for cardiac operation risk evaluation (5±3)scores](P=0.003) were associated with higher BNP level.Postoperative mechanical ventilation time was(15.0±5.4)h,hospital stay was (32±11) d,showed a clear relationship with BNP(P= 0.035,0.001),but postoperative mediastinal infection,atrial fibrillation and mortality of 30 d had no definite relationship with BNP(P>0.05).Conclusion BNP can be used to predict the risk after cardiac surgery.