| 肾动脉变窄和流-固结构相互作用对非Newton脉动流的影响——一个真实的腹部主动脉和肾动脉模型 |
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| 引用本文： | Z·摩塔扎维尼亚,A·扎尔,A·麦迪查德,海治.肾动脉变窄和流-固结构相互作用对非Newton脉动流的影响——一个真实的腹部主动脉和肾动脉模型[J].应用数学和力学,2012,33(2):164-176. |
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| 作者姓名： | Z·摩塔扎维尼亚 A·扎尔 A·麦迪查德 海治 |
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| 作者单位： | 1. 雪拉兹医科大学医学物理与工程研究中心,雪拉兹,伊朗
2. 伊斯兰阿萨德大学雪拉兹分校机械工程系,雪拉兹,伊朗 |
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| 摘 要： | 研究肾动脉狭窄(RAS)对血液流动和血管壁的影响.根据CT扫描图像,重建腹部主动脉和肾动脉的解剖模型,通过模型的脉动流进行了仿真计算,计算中考虑了流体-固体结构的相互作用(FSI).研究RAS对血管壁剪切应力和位移的影响,RAS使得肾动脉中流量减少,肾素-血管紧缩素系统可能被激活,从而导致严重的高血压.
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| 关 键 词： | 肾动脉狭窄 脉动 流体-固体结构的相互作用 非Newton流体 高血压 |
Effects of Renal Artery Stenosis in a Realistic Model of Abdominal Aorta and Renal Arteries Incorporating FSI and Pulsatile Non-Newtonian Blood Flow |
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| Affiliation: | Zahra Mortazavinia1,Amin Zare2,Alireza Mehdizadeh1 (1.Center for Research in Medical Physics and Engineering,School of Medicine, Shiraz University of Medical Science,Shiraz,Iran; 2.Department of Mechanical Engineering,Islamic Azad University,Shiraz Branch, Member of Young Researchers Club,Shiraz,Iran) |
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| Abstract: | The effects of renal artery stenosis(RAS) on blood flow and vessel walls were investigated.Pulsatile blood flow through an anatomically realistic model of abdominal aorta and renal arteries reconstructed from CT-scan images was simulated,incorporating fluid-structure interaction(FSI).In addition to the investigation of RAS effects on wall shear stress and displacement of vessel wall,it was determined that RAS lead to decrease in renal mass flow which may cause the activation of the renin-angiotension system and result in severe hypertension. |
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| Keywords: | renal artery stenosis pulsatile fluid-structure interaction non-Newtonian hypertension |
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