宫颈上皮内瘤变阴道镜下活检与电环切除术后病理的对比分析

目的 对比分析宫颈上皮内瘤变（CIN）阴道镜下活检与电环切除术后病理，提高CIN诊断的准确性。方法 回顾性对比分析216例宫颈上皮内瘤变阴道镜下活检与电环切除术后病理，探讨影响两者符合率的相关因素。结果 两者对比，宫颈电环切除术（LEEP）后病理结果与阴道镜下活检相符的74例，升级的18例，降级的124例。阴道镜下检查不满意者活检与电环切除术后病理对比，升级率大于阴道镜下检查满意者，差异有显著性（P〈0．01）。结论 宫颈转化区向宫颈管上移者，要注意宫颈管内的病变。宫颈电环切除术可以部分弥补阴道镜下活检的缺陷，且有治疗作用。

Pathological comparison of biopsy by colposcopy and loop electrical excision procedure to treat cervical intraepithelial neoplasia

Objective To compare the biopsy by colposcopy and loop electrical excision procedure(LEEP) for cervical intraepithelial neoplasia,and to improve diagnostic accuracy in cervical intraepithelial neoplasia. Methods Biopsy by colposcopy and biopsy after LEEP were analyzed retrospectively in 216 cases of cervical intraepithelial neoplasia to study the related factors of affecting the coincidence rate.Results Comparison of pathological changes following both LEEP and colposcopy showed that 74 cases were the same;18 upgrade;124 downgrade.The upgrade rate of biopsy in satisfactory examination of colposcopy was better than that in dissatisfactory examination.There was significant difference between them(P<0.01). Conclusion An attention should be paid to the endocervical when the transformation zone moves in.LEEP can compensate partially the deficiency of biopsy by colposcopy,and play a therapeutic role.