| 胡桃楸根的化学成分 |
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| 引用本文： | 申健,谭桂山,刘建锋,李福双,李拓颖,徐康平.胡桃楸根的化学成分[J].中国天然药物,2008,6(5):354-356. |
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| 作者姓名： | 申健 谭桂山 刘建锋 李福双 李拓颖 徐康平 |
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| 作者单位： | 中南大学药学院,长沙,410013 |
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| 摘 要： | 目的：对胡桃楸根的化学成分进行分离鉴定。方法：采用硅胶柱层析，重结晶等技术分离纯化化合物；根据理化性质、光谱数据鉴定结构。结果：从胡桃楸根乙醇提取物的石油醚部分中分离得到7个化合物，分别为β-谷甾醇（1）、齐墩果酸（2）、1，8-二羟基-3，7-二甲氧基口山酮（3）、1-羟基-3，7，8-三甲氧基口山酮（4）、α-乳香酸（5）、1，7-二羟基-3，8-二甲氧基口山酮（6）、1，5，8-三羟基-3-甲氧基口山酮（7）。结论：化合物2-7首次从胡桃属分离得到。
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| 关 键 词： | 胡桃楸 胡桃属 口山酮 五环三萜 |
Chemical Constituents from the Roots of Juglans mandshurica Maxim. |
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| SHEN Jian,TAN Gui-Shan,LIU Jian-Feng,LI Fu-Shuang,LI Tuo-Ying,XU Kang-Ping.Chemical Constituents from the Roots of Juglans mandshurica Maxim.[J].Chinese JOurnal of Natural Medicines,2008,6(5):354-356. |
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| Authors: | SHEN Jian TAN Gui-Shan LIU Jian-Feng LI Fu-Shuang LI Tuo-Ying XU Kang-Ping |
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| Affiliation: | (Department of Medicinal Chemistry, School of Pharmaceutical Sciences, Central South University, Changsha, Hunan, 410013, China) |
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| Abstract: | AIM： To investigate the chemical constituents from the roots of Juglans mandshurica Maxim.. METHEDS： The compounds were isolated by silica gel chromatography and recrystallization; their structures were identified on the basis of spectral data and physiochemical properties. RESULTS： Seven compounds were elucidated as β-sitosterol （1）, oleanolic acid （2）, 1, 8-dihydroxy-3, 7-dimethoxyxanthone （3）, 1-hydroxy-3, 7, 8-trimethoxyxanthone （4）, 3α-hydroxy-olean-12-en-24-oic acid （5）, 1, 7-dihydroy-3, 8-dimethoxyxanthone （6）, 1, 5, 8-trihydroxy-3-methoxyxanthone （7）. CONCLUSION：Compounds 2-7 were isolated from genus Juglans L. for the first time. |
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| Keywords: | Juglans mandshurica Maxim Juglans L Xanthones Pentacyclic triterpenoids |
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