轻度认知功能障碍的神经影像学最新研究进展

轻度认知功能障碍(mild cognitive impairment,MCI)是介于正常老化、痴呆之间的一种临床状态,表现为轻度的记忆和智能损害,达不到痴呆诊断标准,但有进展为痴呆的高风险。因此,早发现、早诊断、早治疗非常关键。在MCI的具体诊断上,神经影像诊断表现出显著的临床应用价值,该诊断方式在早期诊断MCI及预防AD疾病的发生上具有显著作用。本文综述了当前国内外应用神经影像学诊断MCI的方法与结果,为进一步诊断及治疗MCI提供依据。

Progress in Neuroimaging of Mild Cognitive Impairment

Mild cognitive impairment (MCI) is an transition state between the cognitive changes
of normal aging and clinical dementia, which is characterized by mild impairment of memory
and intelligence. The general cognitive function and social ability in MCI patients remain intact
and MCI doesn't meet the diagnostic criteria of dementia, while it has a high risk of developing
dementia. Therefore, early detection, early diagnosis and early treatment are crucial for MCI. In
the specific diagnosis of mild cognitive dysfunction, neuroimaging diagnosis has an important
clinical diagnostic value, which plays a critical role in the early diagnosis of MCI and prevention
of Alzheimer's disease. This article reviewed the methods and application of neuroimaging in the
diagnosis of MCI, to provide a reference for clinical diagnosis and treatment of MCI.