| 电刺激对局灶性脑梗死大鼠LINGO1和NgR1表达的影响 |
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| 引用本文： | 王进平,李光勤,马冉冉,米秀娟,黄浩然,李莉. 电刺激对局灶性脑梗死大鼠LINGO1和NgR1表达的影响[J]. 重庆医科大学学报, 2011, 36(1): 42-46 |
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| 作者姓名： | 王进平 李光勤 马冉冉 米秀娟 黄浩然 李莉 |
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| 作者单位： | 1. 重庆医科大学附属第一医院神经内科,重庆,400016
2. 第三军医大学新桥医院疼痛科,重庆,400037 |
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| 摘 要： | 目的:观察电刺激对局灶性脑梗死大鼠缺血侧皮质含亮氨酸重复序列和免疫球蛋白结构域的Nogo受体作用蛋白(LRR and Ig domain-containing,Nogo Receptor-interacting protein,LINGO1)和Nogo-66受体(Nogo-66 receptor,NgR1)表达的影响,...
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| 关 键 词： | 脑梗死 UNGO1 NgR1 电刺激 |
Effect of electrical stimulation on the expressions of LINGO1 and NgR1 in the brain of rats after focal cerebral infarction |
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| WANG Jin-ping,et al. Effect of electrical stimulation on the expressions of LINGO1 and NgR1 in the brain of rats after focal cerebral infarction[J]. Journal of Chongqing Medical University, 2011, 36(1): 42-46 |
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| Authors: | WANG Jin-ping et al |
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| Affiliation: | WANG Jin-ping,et al(Department of Neurology,the First Affiliated Hospital,Chongqing Medical University) |
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| Abstract: | Objective:To explore the mechanism of electrical stimulation improves motor recovery in a rat stroke model.Methods:Spragne-dawley(SD)rats were subjected to establish the stroke model and randomly divieded into ischemic group,electrical stimulation group,sham operation group and normal group.Electrical stimulation was used 90 min after the operation,30 min/d.The expressions of LINGO1 and NgR1 were measured with RT-PCR and immunohistochemistry at 1 d,3 d,7 d,14 d,21 d respectively after the ischemia.Results:M... |
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| Keywords: | cerebral infarction LINGO1 NgR1 electrical stimulation |
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