近十年国内机构发表缺血性卒中研究的国际论文特征分析

目的分析近10年缺血性卒中领域内中国研究者的国际文献情况,为研究者了解该领域的研究热点及方向供参考。方法检索Web of Science TM核心数据库,选择2008-2018年《科学引文索引》(SCI)-Expanded发表论文中中国研究机构的所有缺血性卒中文献,采用文献计量法研究发文时间、发文单位、主要作者、发文期刊及被引用特征,进一步采用CiteSpace软件对该领域国内高被引论文作者、发文的主体特征进行聚类分析及可视化呈现。采用被引用次数、突发性、中心度及Sigma四个文献评价指标对文献进行共被引分析,根据每个聚类中参考文献数量对聚类进行编号,并使用时间线视图展示聚类之间的相互影响和聚类中文献的历史跨度。结果近10年来,国内缺血性卒中领域共发表SCI论文9 401篇,2008年发文量为209篇,2018年发文量达1 710篇,呈上升趋势;发文量由高到低居前5位的单位分别为首都医科大学(1 091篇)、复旦大学(450篇)、上海交通大学(443篇)、香港中文大学(342篇)及南京医科大学(331篇);与国内合作最密切的国外机构是哈佛大学(185篇)。研究主题聚类分析显示,共形成15个聚类,0~14依次为缺血性卒中、卒中保护、缺氧诱导因子1α、球囊支架、染色体区、缺血后适应、缺血卒中风险、多排CT灌注成像、Ⅳ型胶原蛋白标记血管、皮质梗死、平均总梗死体积、核转录因子κB、c-Jun N端蛋白激酶激活、脑微出血、胰岛素抵抗,高被引、高突现值以及高中介中心性值文献主要集中在缺血性卒中、卒中保护两个聚类,而多排CT灌注成像聚类成为近年的研究热点。结论近10年来,中国在缺血性卒中领域的研究越来越多,且具有一定的影响力。缺血性卒中领域的主要研究方向为缺血性卒中、卒中保护、缺氧诱导因子1α、球囊支架、染色体区等,而缺血性卒中、卒中保护及多排CT灌注成像是研究的热点,基于主题的趋势分析有助于了解未来的研究方向。

Literature characteristic of ischemic stroke published in the international journal by Chinese institution in the last decade: a bibliometric analysis

Objective To provide study hotspot and direction of ischemic stroke for peers by reviewing and analyzing the literature characteristic of ischemic stroke published the international journal by Chinese institutions in the last 10 years. Methods We performed literature retrieval in the web of science core database(SCI) from 2008 to 2018, with the search term of "ischemic stroke" and limiting the author institution in China. We used the bibliometric analysis method to investigate the characteristics of the author, publishment time, journal, and citation. The study also used the CiteSpace software to analyze and visualize the cited counts, citation burst, centrality, and sigma value of the citing articles. Results In the past 10 years, 9 401 science citation index(SCI) papers were published in the field of ischemic stroke by Chinese institutions. The number of paper had been increasing annually, and the main institutions of the literation were "Capital Medical university", "Fudan University", "Shanghai Jiaotong University", "Chinese University of Hong Kong" and "Nanjing Medical University". The overseas organization that was the most closely cooperated with Chinese institutions was Harvard University. The cluster analysis of the research topics found fourteen research topics. The ten hottest clusters were "stroke protection", "HIF-1 alpha", "balloon-expandable stents", "chromosome region", "ischemic postconditioning", "ischemic stroke risk", "multidetector CT perfusion", "Collagen Ⅳ-labeled vessel", and "cerebral ischemia". The high cited counts, burst, and centrality of literature were focused on the two clusters of "ischemic stroke" and "stroke protection". The cluster of "multi-slice CT perfusion" has been increased as a hot topic in recent years. Conclusions Many studies on ischemic stroke were published in SCI journal by Chinese researchers in the past ten years, and some studies of those have a great influence on the stroke field. Thematic trend analysis would help to understand future research directions for ischemic stroke.