磷硅酸钠钙对乳牙釉质再矿化作用的研究 |
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引用本文: | 朱顶贵,李姮,俞少玲. 磷硅酸钠钙对乳牙釉质再矿化作用的研究[J]. 实用口腔医学杂志, 2016, 0(1): 104-107. DOI: 10.3969/j.issn.1001-3733.2016.01.022 |
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作者姓名: | 朱顶贵 李姮 俞少玲 |
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作者单位: | 南京大学医学院附属口腔医院·南京市口腔医院儿童口腔科,210008 |
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基金项目: | 南京市医学科技发展专项资金(编号YKK13149) |
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摘 要: | 目的:研究生物活性材料磷硅酸钠钙(CSP)对人工脱矿的乳牙釉质表面再矿化的作用。方法:收集30颗健康离体乳磨牙,将每颗牙冠沿近远中径和颊舌径分成4个釉质块,每个釉质块随机分为4组(n =30)。样本经35%磷酸酸蚀2 min后分别进行如下处理:空白对照(A 组)、0.14%氟化物处理(B 组)、CSP 处理(C 组)、氟化物+CSP 处理(D 组),每天循环处理2次。在10、30 d 时扫描电镜观察釉质表面形态并测定釉质表面显微硬度值(SMH)。结果:扫描电镜观察显示,10 d 时A 组表面呈脱矿的蜂窝状表现,B、C 组脱矿不明显,D 组可见明显的矿化物沉积。30 d 时 A 组可见明显釉质脱矿和釉柱溶解表现,B、C 和 D 组可见程度不等的再矿化。10 d 时 D 组的 SMH 值高于 A 组(P <0.05),30 d 时 B、C、D 组 SMH 值均高于 A组(P <0.05),D 组 SMH 值显著高于 B 和 C 组(P <0.05)。结论:CSP 和氟化物具有促进乳牙釉质再矿化的作用,CSP 和氟化物联合应用优于二者的单独应用。
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关 键 词: | 乳牙 釉质 磷硅酸钠钙(CSP) 再矿化 表面显微硬度 |
The effects of calcium sodium phosphosilicate on the enamel remineralization of primary teeth |
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Abstract: | Objective:To study the effect of calcium sodium phosphosilicate(CSP)on the enamel remineralization of primary teeth. Methods:30 extracted human healthy primary molars were collected.Each tooth was cut bucco-lingually and mesial-distally into 4 sections.The sections were assigned randomly into 4 groups(n =30).Demineralization and remineralization cyclic model was estab-lished by etching with 35% phosphate acid for 2 min and then treated by unexposure of the sample to nothing(control,group A),so-dium monofluorophosphat(MFP,group B),CSP(group C)and MFP +CSP(group D).The cyclic was repeated twice daily for 30 d. The enamel surface morphology was observed by SEM and the surface microhardness(SMH)was measured.Results:On the tenth day,squamous morphology was observed on the enamel surface of group A and that of group D appeared less demineralization.The SMH value of group D was significant higher than that of group A(P <0.05).On the thirtieth day,obvious demineralization was ob-served in group A.Group B,C and D appeared surface remineralization.The SMH value of group B,C and D was significant higher than that of group A(P <0.05).Highest SMH value was achieved in group D.Conclusion:CSP combined with fluoride is more ef-fective in the enamel remineralization of primary teeth than the single application of them. |
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Keywords: | Primary tooth Enamel Calcium sodium phosphosilicate(CSP) Remineralization Surface micro-hardness |
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