早期肠内营养和延迟肠外营养对急性重症胰腺炎肠源性感染患者预后的影响

目的比较早期肠内营养和延迟肠外营养对急性重症胰腺炎肠源性感染患者预后的影响。方法选择2017年1月至2019年12月我院收治的80例急性重症胰腺炎肠源性感染患者作为研究对象,将其随机分为对照组和观察组,每组40例。所有患者均给予常规治疗。在此基础上,对照组给予延迟肠外营养,观察组给予早期肠内营养。比较两组患者治疗前和治疗2周后的白细胞介素-6(IL-6)、C反应蛋白(CRP)、内毒素以及白细胞水平;比较两组的住院时间、治疗费用及不良反应发生情况。结果治疗后,两组的IL-6、CRP、内毒素及白细胞水平均降低,且观察组低于对照组(P<0.05)。观察组的住院时间和治疗费用均明显少于对照组(P<0.05)。观察组的不良反应总发生率低于对照组(P<0.05)。结论早期肠内营养治疗急性重症胰腺炎肠源性感染可促进患者临床指标恢复,缩短住院时间,减轻患者经济负担,并降低不良反应发生率。

Effects of early enteral nutrition and delayed parenteral nutrition on the prognosis of enterogenic infection in patients with severe acute pancreatitis

Objective To compare the effects of early enteral nutrition and delayed parenteral nutrition on the prognosis of enterogenic infection in patients with severe acute pancreatitis.Methods A total of 80 enterogenic infection patients with severe acute pancreatitis admitted in our hospital from January 2017 to December 2019 were selected as the research objects and randomly divided into control group and observation group,with 40 cases in each group.All patients were given conventional treatment.On this basis,the control group was given delayed parenteral nutrition,and the observation group was given early enteral nutrition.The levels of interleukin-6(IL-6),C-reactive protein(CRP),endotoxin and leukocytes were compared between the two groups before treatment and after 2 weeks of treatment;the hospital stay,treatment costs and adverse reactions of the two groups were compared.Results After treatment,the levels of IL-6,CRP,endotoxin and leukocytes in the two groups decreased,and those in the observation group were lower than the control group(P<0.05).The hospital stay and treatment costs of the observation group were significantly less than those of the control group(P<0.05).The total incidence of adverse reactions in the observation group was lower than that in the control group(P<0.05).Conclusion Early enteral nutrition in the treatment of enterogenic infection patients with severe acute pancreatitis can promote the recovery of clinical indicators,shorten the hospital stay,reduce the economic burden and the incidence of adverse reactions of patients.