| Role of the Pericytes of Intra－acinar Pulmonary Artery in the Structural Remodeling of Pulmonary Vessels |
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| 引用本文： | 吴永平,车东媛,张婉蓉,李文英. Role of the Pericytes of Intra－acinar Pulmonary Artery in the Structural Remodeling of Pulmonary Vessels[J]. 华中科技大学学报(医学英德文版), 1995, 15(1): 16-18. DOI: 10.1007/BF02887878 |
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| 作者姓名： | 吴永平 车东媛 张婉蓉 李文英 |
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| 作者单位： | Department of Pathology，Tongji Medical University，Wuhan |
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| 摘 要： | （吴永平）（车东媛）（张婉蓉），（李文英）ＲｏｌｅｏｆｔｈｅＰｅｒｉｃｙｔｅｓｏｆＩｎｔｒａ－ａｃｉｎａｒＰｕｌｍｏｎａｒｙＡｒｔｅｒｙｉｎｔｈｅＳｔｒｕｃｔｕｒａｌＲｅｍｏｄｅｌｉｎｇｏｆＰｕｌｍｏｎａｒｙＶｅｓｓｅｌｓ￥ＷＵＹｏｎｇ－ｐｉｎｇ；Ｃ...
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| 收稿时间： | 1994-09-29 |
Role of the pericytes of intra-acinar pulmonary artery in the structural remodeling of pulmonary vessels |
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| Wu Yong-ping,Che Dong-yuan,Zhang Wan-rong,Li Wen-ying. Role of the pericytes of intra-acinar pulmonary artery in the structural remodeling of pulmonary vessels[J]. Journal of Huazhong University of Science and Technology. Medical sciences, 1995, 15(1): 16-18. DOI: 10.1007/BF02887878 |
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| Authors: | Wu Yong-ping Che Dong-yuan Zhang Wan-rong Li Wen-ying |
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| Affiliation: | (1) Department of Pathology, Tongji Medical University, Wuhan |
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| Abstract: | Whether or not the pericytes exist in the intra-acinar pulmonary arteries and their normal structure and morphological changes during development of the structural remodeling of pulmonary vessels were observed using a pulmonary hypertension model in rats induced by monocrotaline injection.The results showed that the pericytes in the peripheral pulmonary vessels proliferated and transformed into smooth muscle cells during development of pulmonary hypertension,and at the same time,the pericytes could synthesize and secrete extracellular matrix including collagen,suggesting that the pericytes play an important role in the development of pulmonary hypertension and structural remodeling of the pulmonary vessels. |
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| Keywords: | hypertension pulmonale pericyte artery pulmonale |
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