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黄芪水煎液对肿瘤患者放疗所致骨髓抑制的作用
引用本文:邹丹,全宏勋,胡群员,于静,马新峰.黄芪水煎液对肿瘤患者放疗所致骨髓抑制的作用[J].郑州大学学报(医学版),2003,38(2):218-219.
作者姓名:邹丹  全宏勋  胡群员  于静  马新峰
作者单位:1. 河南职工医学院组织学与胚胎学教研室,郑州,450003
2. 河南省人民医院内科,郑州,450003
基金项目:河南省科技攻关基金资助项目9512 0 0 50 0
摘    要:目的:探讨黄芪水煎液对肿瘤患者放疗所致骨髓抑制的作用。方法:128例恶性肿瘤经放疗后引起骨髓抑制患者,随机分为试验组(68例)和对照组(60例),分别应用黄芪水煎液和鲨肝醇治疗,观察2组临床症状、外周血白细胞及免疫功能的变化。结果:黄芪水煎液可明显改善临床症状,有效率为100%,升高外周血白细胞,有效率为89.7%;对照组有效率分别为76.7%和53.3%,2组比较差异有统计学意义,P均<0.01。同时黄芪水煎液还能提高机体免疫功能,可明显升高患者血中Tc、Th、IgG、IgM和C3水平。结论:黄芪水煎液对肿瘤放疗引起的骨髓抑制具有治疗作用。

关 键 词:黄芪水煎液  肿瘤  放疗  骨髓抑制
修稿时间:2002年8月26日

Effects of radix astragali on the myelosuppression induced by irradiation in patients with cancer
ZOU Dan ,QUAN Hongxun ,HU Qunyuan ,YU Jing ,MA Xinfeng.Effects of radix astragali on the myelosuppression induced by irradiation in patients with cancer[J].Journal of Zhengzhou University: Med Sci,2003,38(2):218-219.
Authors:ZOU Dan  QUAN Hongxun  HU Qunyuan  YU Jing  MA Xinfeng
Affiliation:ZOU Dan 1),QUAN Hongxun 1),HU Qunyuan 1),YU Jing 2),MA Xinfeng 1) 1)Department of Histology and Embryology,Henan Medical College for Staff and Workers,Zhengzhou 450003 2)Department of Internal Medicine,Henan Provincial People's Hospital,Zhengzhou 450003
Abstract:Aim:To study the effects of radix astragali (RA) on the myelosuppression induced by irradiation.Metheods:A total of 128 cancer patients whose WBC were low after radiotherapy were randomly allocated into 2 groups.RA extract and an antagonistic myelosuppression drug were given to the animals in the treatment group ( n =68) and the controls ( n =60), respectively. The clinical symptoms,the peripheral WBC count,and immune function were observed.Results:Compared with control group, the effective rate of improving clinical symptoms was 100%,and that of increasing WBC count was 89.7% in the treatment group, and immune function was improved with the increase of Tc,Th,IgG,IgM and C3 in blood.Conclusions:RA has antagonistic effects on the myelosuppression induced by cancer irradiation.
Keywords:radix astragali  irradiation  myelosuppression  neoplasm  
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