2型糖尿病伴慢性牙周炎牙周基础治疗的疗效观察

目的观察牙周基础治疗对2型糖尿病伴慢性牙周炎患者在临床指标及血糖控制方面的影响。方法选取52例2型糖尿病伴慢性牙周炎患者并随机分为2组。实验组行牙周基础治疗和药物治疗，对照组仅给予药物治疗。治疗前后分别记录患者各项临床指标和糖化血红蛋白水平。结果治疗后16周实验组菌斑指数（PLI）及出血指数显著减少，且PLI与对照组差异有统计学意义（P〈0.001）：两组患者其他各项临床指标和糖化血红蛋白水平在治疗后有一定改善，但差异无统计学意义。结论牙周基础治疗有利于2型糖尿病伴慢性牙周炎患者减轻牙周炎症及在一定程度上改善代谢状况。

Effect of initial periodontal therapy on patients with type 2 diabetes mellitus

Objective To evaluate the effect of initial therapy on the control of clinical variables and blood glucose level on type 2 diabetic patients with chronic periodontitis. Methods Fifty-two type 2 diabetic patients with chronic periodontitis were randomized into two groups (group A and group B). Treatment including scaling and root planning with systemic use of doxycycline were given to patients in Group A, while patients in Group B were only provided ith systemic use of doxycycline. Clinical variables and glycated hemoglobin were assessed before and after the treatment. Results 16 weeks after therapy, group A had a statistically significant reduction on plaque index and bleeding on probing (P ＜ 0.001), with a significant difference in plaque index between the two groups (P ＜ 0.001). Some improvements were observed on other clinical variables and glycated hemoglobin (HbA1c) level in both groups althongh statistical significance was not detected (P ＞ 0.05). Conclusion This study suggests that initial therapy is of value in maintaining periodontal health and may be beneficial to the reduction of blood glucose level in type 2 diabetic patients with chronic periodontitis.