妊娠期急性胰腺炎12例临床分析

目的 探讨妊娠期急性胰腺炎的病因、发病机制、诊断、综合治疗、预防及预后。方法 对我院1999年4月至2004年4月收治的12例妊娠期急性胰腺炎的临床资料进行回顾性分析。结果 12例妊娠期急性胰腺炎非手术治疗10例，手术治疗1例，内镜十二指肠乳头括约肌切开(EST) 鼻胆管引流治疗1例。治愈11例(91．7％)，死亡1例(8、3％)。终止妊娠2例。11例胎儿存活。结论 胆道疾病与高脂血症是妊娠期急性胰腺炎的主要病因。妊娠期急性胰腺炎临床症状不典型，对母婴威胁极大。及时、准确的诊断与治疗是此病预后的关键，妊娠期急性胰腺炎主要采用非手术疗法。终止妊娠时机及方法应遵循个体化治疗原则。

Clinical analysis of acute pancreatitis in pregnancy with 12 cases report

Objective To explore the etiology,mechanism,diagnosis,treatment,prevention and prognosis of acute pancreatitis in pregnancy(APIP).Methods Twelve patients with APIP treated in our hospital from April,1999 to April,2004 were analyzed retrospectively.Results Among 12 cases of APIP,10 cases received non-operative therapy,1 case received operative therapy,1 case received endoscopic sphincterotom(EST).11 cases (91.7%) recovered and 1 case (8.3%) died.2 cases received termination of pregnancy.All the 11 fetus survived.Conclusion Cholelithiasis and hyperlipemia are the main reasons of APIP.APIP has no classical symptom and it threatens the lives of mother and fetus seriously.The correct diagnosis and proper treatment are of great importance to the prognosis of APIP.APIP should mainly be treated by non-operative measures.The timing and method of termination of pregnancy should follow according to individualized therapy principles.