肺功能检测在小儿呼吸道疾病中的临床应用

目的:分析和评估肺功能检测在小儿呼吸道疾病中的临床价值.方法:采用便携式肺功能仪检测6 261例呼吸道疾病患儿.部分病例定期随访,对其中268例咳嗽变异性哮喘儿童(CVA),147例哮喘儿童(AS)治疗前后进行第1秒用力呼气容积(FEV1),用力肺活量(FVC),组变异率(PEFR)的自身对照,以及咳嗽变异性哮喘与哮喘儿童肺功能比较.结果:哮喘儿童经糖皮质激素气雾剂治疗后肺功能明显改善,治疗前FEV1(1.029±0.398)L,治疗后( 1.180±0.427)L,治疗前FVC(1.147±0.468)L,治疗后(1.318±0.480)L,P ＜0.001.咳嗽变异性哮喘与哮喘儿童肺功能变化一致,咳嗽变异性哮喘组PEFR大于15% 13 2例,小于15% 136例,哮喘儿童组大于15% 68例,小于15% 79例,P>0.05.结论:肺功能检测是诊断哮喘必不可少的手段,为指导治疗,判断预后,评价疗效提供可靠的依据,应广泛推广于儿科临床.

Analysis of lung function in children with respiratory diseases and its clinical application

Objective: To evaluate the clinical application of lung function analysis in diagnosis of children respiratory diseases. Methods: Respiratory function was evaluated with portable lung function detector in 6 261 children with respiratory diseases.FEV_(1),FVC and PEFR were measured in 268 children with cough variant asthma (CVA) and 147 children with asthma (AS),and the results were self-compared during follow-up. Results: There were no significant differences in above parameters between children with cough variant asthma and those with asthma (P>0.05).Lung functions of asthma children were improved evidently by administration of glycocorticoid inhalator (P<0.001). Conclusion: Lung function detection is essential for diagnosis of asthma and it can be used as a reliable index for therapeutic effect of asthma children.[