脑梗死与颈动脉粥样硬化斑块的相关性分析

目的探讨C-反应蛋白(CRP)、血脂、尿酸(UA)、纤维蛋白原(FIB)水平及颈动脉粥样硬化与脑梗死(CAS)斑块的关系。方法选取我院2008-12一2011-10神经内科脑梗死患者78例作为观察组,78例健康体检者设为对照组,检测2组血脂、FIB、UA及CRP水平。结果观察组CAS斑块检出率为77.78%高于对照组的19.77%,差异有统计学意义(P<0.01)。观察组血清总胆固醇(TC)、低密度脂蛋白(LDL)、纤维蛋白原(FIB)、尿酸(UA)、C-反应蛋白(CRP)水平明显高于对照组(P<0.05)。结论 CAS斑块是脑梗死发生的重要因素,TC、LDL、FIB、UA及CRP水平增高是脑梗死及CAS斑块形成的危险因素。

Correlation analysis of cerebral infarction and carotid atherosclerotic plaques

Objective To investigate the correlation of the levels of C-reactive protein(CRP),lipids,uric acid(UA),fibrinogen(FIB) and carotid artery atherosclerotic plaques and cerebral infarction(CAS).Methods From December 2008 to October 2011,78 cases patients with cerebral infarction in our hospital as the observation group,78 cases of healthy persons was set as the control group,the FIB,UA and CRP levels were detected.Results The observation group CAS plaque detection rate was 77.78%,which was higher than 19.77% in control group,the difference was statistically significant(P<0.01).The serum total cholesterol(TC),low density lipoprotein(LDL),fibrinogen(FIB),uric acid(UA),C-reactive protein(CRP) levels were significantly higher than those in control group(P<0.05).Conclusion CAS plaque is an important factor in cerebral infarction,and can increase TC,LDL,FIB,UA and CRP levels;it is a risk factor for cerebral infarction and CAS plaque.