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不同产地白芍HPLC指纹图谱及芍药苷和芍药内酯苷含量的比较研究
引用本文:朱如彩,蔡萍,李雅,李芳荣. 不同产地白芍HPLC指纹图谱及芍药苷和芍药内酯苷含量的比较研究[J]. 湖南中医药大学学报, 2012, 32(3): 34-37
作者姓名:朱如彩  蔡萍  李雅  李芳荣
作者单位:湖南省中医药研究院中药研究所,湖南长沙,410013
基金项目:湖南省科学技术厅科技计划项目
摘    要:目的 建立湘白芍、毫白芍与抗白芍HPLC指纹图谱分析方法,并对3种不同产地药材进行主要化学成分的比较.方法 采用HPLC对11批白芍样品进行指纹图谱分析,并测定了主要化学成分芍药苷和芍药内酯苷的含量.结果 所建立的方法精密度、稳定性和重现性良好;11批白芍样品的指纹图谱有8个共有峰.结论 通过建立白芍指纹图谱的定性、芍药苷及芍药内酯苷的定量,为白芍的质量控制提供了更为全面的方法.

关 键 词:HPLC  指纹图谱  白芍  芍药苷  芍药内酯苷

Comparative study of HPLC fingerprints and Paeoniflorin and Albiflorin contents in Paeoniae Radix Alba from different regions
ZHU Ru-cai , CAI Ping , LI Ya , LI Fang-rong. Comparative study of HPLC fingerprints and Paeoniflorin and Albiflorin contents in Paeoniae Radix Alba from different regions[J]. Journal of Traditional Chinese Medicine University of Hunan, 2012, 32(3): 34-37
Authors:ZHU Ru-cai    CAI Ping    LI Ya    LI Fang-rong
Affiliation:(Institute of Chinese Materia Medica,TCM Academy of Hunan,Changsha,Hunan 410013,China)
Abstract:Objective To establish HPLC fingerprints method and compare the main chemical constituents of Paeoniae Radix Alba from Hunan,Anhui and Zhejiang.Methods The fingerprints of 11 Paeoniae Radix Alba samples from different regions are analyzed by HPLC method.The contents of main chemical constituents such as Paeoniflorin and Albiflorin were analyzed.Results The established method is of good precision,stability and reproducibility.The fingerprints of the 11 samples of Paeoniae Radix Alba share 8 same peaks.Conclusion The established method in this study on fingerprints of Paeoniae radix Alba in qualitatively and content of Paeoniflorin and Albiflorin in quantitatively has provided a more comprehensive means for the quality control of Paeoniae Radix Alba.
Keywords:HPLC  fingerprint  Paeoniae Radix Alba  paeoniflorin  albiflorin
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