| 冠心病患者载脂蛋白AV与脂蛋白(a)关系研究 |
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| 引用本文： | 何成毓,林玲,李洁琪.冠心病患者载脂蛋白AV与脂蛋白(a)关系研究[J].临床心血管病杂志,2011,27(4). |
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| 作者姓名： | 何成毓 林玲 李洁琪 |
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| 作者单位： | 1. 海南省第三人民医院心内科,海南三亚,572000
2. 贵州省贵阳医学院附属医院心内科 |
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| 摘 要： | 目的:探讨冠心病患者血清载脂蛋白AV(ApoAV)与脂蛋白(a)LP(a)]之间的关系.方法:入选120例住院患者均接受冠状动脉造影检查,根据造影结果分为冠心病组60例和对照组60例,所有患者均测定空腹血糖(FBG)、血清TC、TG、HDL-C、LDL-C、载脂蛋白A1(ApoAI)、载脂蛋白B(ApoB)与LP(a);同时采用酶联免疫吸附法测定血清ApoAV.所有资料均进行正态性检验.结果:冠心病组血清ApoAV、ApoAI、HDL-C显著低于对照组(206.76±135.95)μg/L∶(265.33±122.35)μg/L],(1.09±0.26)g/L∶(1.23±0.25)g/L],(1.22±0.29)mmol/L∶(1.31±0.21)mmol/L],P<0.01;TG、LP(a)高于对照组(1.64±1.15)mmol/L∶(1.10±0.37)mmol/L],(393.03±280.08)mg/L∶(218.37±60.58)mg/L],P<0.01.ApoAV与TG、LP(a)呈负相关,与HDL-C呈正相关.结论:冠心病患者血清ApoAV降低、LP(a)增高.ApoAV与LP(a)对冠心病的发展影响不同.
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| 关 键 词： | 冠心病 载脂蛋白 脂蛋白(a) |
The correlation between serum concentrations of apolipoprotein AV and level of Lipoprotein(a) in patients with coronary heart disease |
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| HE Chengyu,LIN Ling,LI Jieqi.The correlation between serum concentrations of apolipoprotein AV and level of Lipoprotein(a) in patients with coronary heart disease[J].Journal of Clinical Cardiology,2011,27(4). |
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| Authors: | HE Chengyu LIN Ling LI Jieqi |
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| Affiliation: | HE Chengyu1 LIN Ling1 LI Jieqi2(1Department of Cardiology,the Third People's Hospital of Hainan Province,Sanya,Hainan,572000,China,2Department of Cardiology,the Affiliated Hospital of Guiyang Medical College) |
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| Abstract: | Objective:To explore The correlation between serum concentrations of apolipoprotein AV and level of Lipoprotein(a) in patients with coronary heart disease(CHD).Method:The level of serum total cholesterol(TC),triglyceride(TG),high-density lipoprotein cholesterol(HDL-C),low density lipoprotein cholesterol(LDL-C),apolipoprotein A1(ApoA1),apolipoprotein B(ApoB) and Lipoprotein(a) were examined in 120 individuals by biochemistry department;enzyme-linked immunosorbent assay(ELISA) method was used to determine Apo... |
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| Keywords: | coronary heart disease apolipoproteins lipoprotein(a) |
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