| 温郁金中倍半萜类成分的分离与鉴定 |
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| 引用本文： | 楼燕,何昊,魏星川,李雪改,陈丽霞,邱峰.温郁金中倍半萜类成分的分离与鉴定[J].沈阳药科大学学报,2010,27(3):195-199. |
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| 作者姓名： | 楼燕 何昊 魏星川 李雪改 陈丽霞 邱峰 |
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| 作者单位： | （沈阳药科大学 中药学院， 辽宁 沈阳 110016） |
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| 摘 要： | 目的对温郁金(Curcuma wenyujin)的化学成分进行研究。方法采用硅胶柱色谱、ODS柱色谱、Sephadex LH-20柱色谱,HPLC以及制备薄层色谱(P-TLC)进行分离和纯化,并依据理化性质和光谱学分析鉴定其化学结构。结果从温郁金的体积分数为50%的乙醇溶液提取物中分离得到6个倍半萜,分别鉴定为原莪术醇(procurcumenol,1)、环氧泽泻烯(alismoxide,2)、aeruginolac-tone(3)、(1E,4Z)-8-hydroxy-6-oxogermacra-1(10),4,7(11)-trieno-12,8-lactone(4)、1β,4α-di-hydroxy-5α,8β(H)-eudesm-7(11Z)-en-12,8-olide(5)和curcolonol(6)。结论其中化合物1、2为愈创木烷型倍半萜,3、4为吉玛烷型倍半萜,5、6为桉烷型倍半萜。化合物4、5均为首次从该属植物中分离得到,化合物1、2、3、6均为首次从本植物中分离得到。
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| 关 键 词： | 温莪术 化学成分 愈创木烷 吉玛烷 桉烷型 倍半萜 |
| 收稿时间： | 2009-4-23 |
Sesquiterpenes from Curcuma wenyujin |
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| LOU Yan,HE Hao,WEI Xing-chuan,LI Xue-gai,CHEN Li-xia,QIU Feng.Sesquiterpenes from Curcuma wenyujin[J].Journal of Shenyang Pharmaceutical University,2010,27(3):195-199. |
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| Authors: | LOU Yan HE Hao WEI Xing-chuan LI Xue-gai CHEN Li-xia QIU Feng |
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| Affiliation: | LOU Yan,HE Hao,WEI Xing-chuan,LI Xue-gai,CHEN Li-xia,QIU Feng(School of Traditional Chinese Materia Medica,Shenyang Pharmaceutical University,Shenyang,110016,China) |
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| Abstract: | Objective To study the chemical constituents from the dried rhizomes of Curcuma wenyujin Y.H.Chen et C.Ling.Methods The constituents were purified by repeated column chromatography,including Silica gel,Sephadex LH-20 column,ODS column,HPLC and preparative-TLC(P-TLC).The structures of these compounds were elucidated by spectroscopic methods.Results Six sesquiterpenes were isolated from the dried rhizomes of C.wenyujin and identified as procurcumenol(1),alismoxide(2),aeruginolactone(3),(1E,4Z)-8-hydroxy-6-oxo... |
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| Keywords: | Curcuma wenyujin chemical constituent guaiane germacrane eudesmane sesquiterpene |
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