药物联合功能性内镜鼻窦手术治疗中重度不伴鼻息肉慢性鼻-鼻窦炎的疗效观察

目的 探讨药物、功能性内镜鼻窦手术综合治疗中-重度不伴鼻息肉慢性鼻-鼻窦炎的疗效.方法 收集2015年10月至2016年10月入院的66例中-重度不伴鼻息肉的慢性鼻-鼻窦炎患者随机分为两组,药物组患者给予单独药物治疗,综合组患者则给予药物、功能性内镜鼻窦手术综合治疗,比较两组患者总体治疗效果、治疗前后主客观疗效与局部疼痛情况.结果 综合组患者治愈率显著优于药物组(84.8％比45.5％),两组比较差异有统计学意义(P＜0.01);治疗后综合组SNOT-20评分[(7.06±3.62)比(14.39±6.04)]与Lund-Kennedy评分[(1.12±0.57)比(2.35±1.38)]显著低于药物组,面颊部VAS评分[(0.38±0.22)比(1.24±0.70)]与头部VAS评分[(0.69±0.58)比(1.53±0.96)]显著低于药物组,两组比较差异均有统计学意义(均P＜ 0.01).结论 药物、功能性内镜鼻窦手术综合治疗中-重度不伴鼻息肉慢性鼻-鼻窦炎的疗效显著,具有借鉴意义.

Effect of drug combined with functional endoscopic sinus surgery in the treatment of moderate to severe chronic rhinosinusitis without nasal polyps

Objective To investigate the efficacy of drug combined with functional endoscopic sinus surgery in the treatment of moderate to severe chronic rhinosinusitis without nasal polyps.Methods 66 patients with moderate to severe chronic rhinosinusitis without nasal polyps from October 2015 to October 2016 were randomly divided into two groups.The patients in the drug group were treated with drug alone,while the patients in the combined group were treated with drug combined with ftmctional endoscopic sinus surgery.The overall treatment effect,subjective and objective effects,and local pain of the two groups were compared.Results The cured rate of the combined group was significantly better than that of the drug group (84.8％ vs.45.5％),with statistically significant difference (P＜0.05).After treatment,SNOT-20 score and Lund-Kennedy score of the combined group were significantly lower than those of the drug group [(7.06±3.62) vs.(14.39±6.04),(1.12±0.57) vs.(2.35±1.38)],cheek VAS score and head VAS score of the combined group were significantly lower than those of the drug group [(0.38±0.22) vs.(1.24±0.70),(0.69±0.58)vs.(1.53±0.96)],with statistically significant differences (P＜0.05).Conclusion Drug combined with functional endoscopic sinus surgery is effective in the treatment of moderate to severe chronic rhinosinusitis without nasal polyps.