冠心病与巨细胞病毒初期感染的相关性研究 |
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引用本文: | 温应方,刘子峰,刘桂荣,黎灵峰. 冠心病与巨细胞病毒初期感染的相关性研究[J]. 医学新知杂志, 2011, 21(4): 272-274 |
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作者姓名: | 温应方 刘子峰 刘桂荣 黎灵峰 |
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作者单位: | 梅县人民医院检验科,广东梅州,514011 |
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摘 要: | 目的探讨人类巨细胞病毒初期感染与冠心病发生发展的关系。方法用捕获ELISA法检测血清HCMV—IgM,酶法检测血脂4项,免疫比浊法检测C-反应蛋白(CRP),并进行比较。结果冠心病组(61例)、健康对照组(44例)和其他疾病组(48例)的HCMV—IgM阳性率分别为8.20%、2.27%和4.17%,冠心病组与对照组之间无统计学差异(P〉0.05);冠心病组血脂4项和CRP均高于健康对照组,有统计学差异(P〈0.05)。结论尚不能认为冠心病与巨细胞病毒初期感染有关。
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关 键 词: | 巨细胞病毒 IgM 冠心病 感染 |
Correlation between Coronary Artery disease and HCMV Incipient ilnfection |
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Affiliation: | Wen Yingfang, Liu Zifeng, Liu Guirong, et al( Department of Medical Laboratory, Meixian People's Hospital, Meizhou, Guangdong ,514011) |
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Abstract: | Objective To investigate the correlation between the occurrence and development of coronary artery disease(CAD) and HCMV incipient infection. Methods The levels of HCMV - IgM were detected in serum samples of 61 CAD patients,44 healthy individuals and 48 patients without cardiovascular disease and diabetes mellitus by using enzyme -linked immunosorbent assay(ELISA) ,and four indexes of lipoid and C reactive protein(CRP) were detected in serum at the same time. Results The positive rates of HCMV - IgM in CAD group, heathlthy individuals and control group without cardiovascular disease and diabetes mellitus were 8.20% ( 5/61 ) , 2.27% ( 1/44 ) and 4.17% (2/48),respectively. There were no significant difference between the CAD group with control group( x^2 = 1. 970,P = 0. 374). The level of four indexes of lipoid and C reactive protein (CRP) of CAD group were higher than control group(P 〈 0.05). Conclusion The present study does not suggest that coronary artery disease is associated with HCMV incipient infection. |
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Keywords: | Human cytomegalovirus IgM Coronary atherosclerotic heart disease Infection |
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