Multiple primary malignant neoplasms in urologic patients |
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Authors: | Osman Inci Esat Kaya Bulent Alagol Irfan Huseyin Atakan Sabahattin Aydin Hasan Ereselli |
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Affiliation: | (1) Department of Urology, Trakya University Medical Faculty Hospital, Edirne, Turkey;(2) Altinkoy Sitesi B-blok Daire:3 Kutlutas, 22030 Edirne, Turkey |
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Abstract: | Methods: Second primary cancers constitute approximately 9–10% of malignancies diagnosed in the United States. We aimed to show the
risk and incidance of second primary tumor occuring associated to urologic tumors and show the distrubution of tumors in Tracia
region. We retrospectively examined the patients' files with the diagnosis of malignant disease between the years 1985–2000.
Hazard function analysis was performed to estimate the relative risk of secondary malignancy occuring. Age, sex and tumor
number were examined to find out if they affect on mortality rate. Results: A total number of 25 MPMNs were diagnosed. In 52 percent of the cases the second primary neoplasm developed within six months.
The relative risk of development of a second neoplasm is found as increasing 1.111 times per month. The incidence of secondary
malignancy occuring in the patients with one tumor was found as 6.31%. Age (p < 0.001) and tumor number (p < 0.001) are found as statistically effective predictor on mortality rate where the sex is not. Conclusions: In the patients with a primary tumor not only the metastasis must be investigated but also second primary tumors should be
taken in to consideration.
This revised version was published online in August 2006 with corrections to the Cover Date. |
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Keywords: | Multiple primary neoplasms Second primary malignancy Urologic cancer |
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